文章摘要

18F-FDG PET/CT对骨与软组织肿瘤的诊断价值

作者: 1,2唐光, 1陈飞
1 中南大学湘雅二医院脊柱外科，长沙 410000
2 湘南学院附属医院脊柱外科，湖南 郴州 423000
通讯: 陈飞 Email: chenfei1972@csu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2022.07.012
基金: 郴州市技术创新引导项目(lcyl2021099)。

摘要

目的：评价氟18-脱氧葡萄糖(18F-fluorodeoxyglucose，18F-FDG)在骨与软组织肿瘤病变诊治过程中的价值，利用糖代谢参数为骨与软组织肿瘤提供新的临床治疗依据。方法：回顾性分析2013年8月至2021年10月在中南大学湘雅二医院和湘南学院附属医院行18F-FDG正电子发射断层扫描/计算机断层扫描成像(positron emission tomography/computed tomography，PET/CT)检查且经病理证实的骨及软组织肿瘤或炎症改变的57例患者的临床资料及影像学资料。结果：间叶源性骨恶性肿瘤、孤立性浆细胞瘤、骨转移瘤与炎性病变均为FDG阳性，代谢体积(metabolic tumour volume，MTV)与病变部位总糖酵解量(total lesion glycolysis，TLG)在间叶源性骨肿瘤与炎性改变间差异有统计学意义。结论：18F-FDG PET/CT的MTV与TLG等代谢参数在骨及软组织肿瘤早期诊断中有较高价值。
关键词： 骨肿瘤；18F-FDG；正电子发射断层扫描/计算机断层扫描成像；标准摄取值

Diagnostic value of 18F-FDG PET/CT in bone and soft tissue tumors

Authors: 1,2TANG Guang, 1CHEN Fei
1 Department of Spinal Surgery, Second Xiangya Hospital Affiliated to Central South University, Changsha 410000, China
2 Department of Spine Surgery, Affiliated Hospital of Xiangnan University, Chenzhou Hunan 423000, China

CorrespondingAuthor: CHEN Fei Email: chenfei1972@csu.edu.cn

DOI: 10.3978/j.issn.2095-6959.2022.07.012

Foundation: This work was supported by Chenzhou Technological Innovation Guidance Project, China (lcyl2021099).

Abstract

Objective: To evaluate the value of 18F-fluorodeoxyglucose (18F-FDG) in the diagnosis and treatment of bone and soft tissue tumors, and to provide a new clinical basis by using glucose metabolism parameters. Methods: The clinical and imaging data of 57 patients with bone and soft tissue tumors or inflammatory changes confirmed by pathology and by positron emission tomography/computed tomography (PET/CT) in the Second Xiangya Hospital of Central South University and the Affiliated Hospital of Xiangnan University from August 2013 to October 2021 were analyzed retrospectively. Results: FDG was positive in mesenchymal malignant tumors, solitary plasmacytomas, bone metastases, and inflammatory lesions. There was significant difference in MTV and TLG between mesenchymal bone tumors and inflammatory lesions. Conclusion: 18F-FDG PET/CT has high value in the early diagnosis of bone and soft tissue tumors by using metabolic parameters such as MTV and TLG.

Keywords： bone tumor; 18F-FDG; positron emission tomography/computed tomography; standardized uptake value

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