Deep venous thrombosis (DVT) of iliac vein compression is a common DVT of lower limb in clinic, which usually occurs in the left lower limb. With the increased morbidity of DVT of the lower extremity, it is particularly important for us to deepen the cognition and treatment about this disease. Because its complications not only are one of the common preventable causes of deaths in hospital, but also the inducement of many potential long-term diseases. Timely and correct diagnosis and treatment are especially important to prevent the continued expansion of thrombosis. Vascular surgery combined with interventional therapy and the development of scientific and technological research, vascular surgeons are familiar with endovascular operations such as filter implantation, thrombosis aspiration, balloon dilation, stent implantation and retrievable filter removal. The establishment of new treatment thinking and the mature application of clinical technology have greatly improved the medical experience of the affected limb and the advantages of patient compliance, shorten the length of hospital stay, and less trauma to patients, etc.