文章摘要

岩藻黄质及其活性

作者: 1,2方学红, 3李晓丹, 1,2蒋代顺, 3林杰, 1,2张妍, 2刘义
1 广东医科大学(湛江校区)药学院,广东 湛江 524023
2 广东医科大学广东天然药物研究与开发实验室,广东 湛江 524023
3 广东医科大学药学院(东莞校区),广东 东莞 523808
通讯: 刘义 Email: plliu78@sina.com
DOI: 10.3978/j.issn.2095-6959.2022.05.031

摘要

岩藻黄质(fucoxanthin,FX)是一种广泛存在于藻类和无脊椎的动物中的海洋活性物质,它的特点是分子质量小,化学活性强,易氧化,容易被生物体吸收,对皮肤细胞、肝、肾、脾和组织没有毒性。自从FX被发现后,它的安全性得以证实,其在体内和体外的代谢、不同的提取工艺及活性被研究,FX因其显著的活性,目前已经被用于临床试验和产品开发。研究表明FX具有开发为临床用药的潜力。
关键词: 岩藻黄质;药理活性;海洋活性物质

Fucoxanthin and its activity

Authors: 1,2FANG Xuehong, 3LI Xiaodan, 1,2JIANG Daishun, 3LIN Jie, 1,2ZHANG Yan, 2LIU Yi
1 School of Pharmacy, Guangdong Medical University (Zhanjiang Campus), Zhanjiang Guangdong 524023, China
2 Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University, Zhanjiang Guangdong 524023, China
3 School of Pharmacy, Guangdong Medical University (Dongguan Campus), Dongguan Guangdong 523808, China

CorrespondingAuthor: LIU Yi Email: plliu78@sina.com

DOI: 10.3978/j.issn.2095-6959.2022.05.031

Abstract

Fucoxanthin is a marine active material, which it’s widely found in algae and invertebrate animals. It is characterized by small molecular weight, intense chemical activity, easy oxidation, easy to be absorbed by the organism body. Fucoxanthin is not toxic to human skin cells, liver, kidney, spleen and glandular tissue. Since its discovery, its safety has been verified, and in vivo and in vitro, different extraction processes and activities have been studied. Because of the significant activity of fucoxanthin, clinical trials and product development have been started. Evidence of fucoxanthin activity suggests that it also offers the opportunity to be developed for other clinical applications. In this essay, it will provide an overview of the above content. It provides a better basis for development as products, which are used to treat more diseases.
Keywords: fucoxanthin; pharmacological activities; marine active substances

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