氯化钆药理作用研究进展
作者: |
1张雨,
1蔡莉
1 哈尔滨医科大学附属肿瘤医院内四科,哈尔滨 150040 |
通讯: |
蔡莉
Email: caili@ems.hrbmu.edu.cn |
DOI: | 10.3978/j.issn.2095-6959.2015.02.031 |
基金: | 国家自然科学基金面上项目, 81172214 |
摘要
钆为一种稀有金属,现被广泛用于实验研究。近年来通过对动物实验研究发现:氯化钆具有抑制 肿瘤侵袭转移、减轻缺血再灌注损伤、抑制免疫炎症反应等保护作用。本文总结国内外氯化钆对 治疗疾病及其药理作用的研究进展,以期能够对该领域有一个较为全面的认识,为治疗某些疾病 寻找新的线索和突破口。
关键词:
氯化钆
肿瘤
再灌注损伤
免疫炎症
Progress of the pharmacological effects of gadolinium chloride
CorrespondingAuthor: CAI Li Email: caili@ems.hrbmu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2015.02.031
Abstract
Gadolinium, a rare-earth metal, has been widely used in experimental study. In recent years, the study of animal experiments has shown that gadolinium chloride could inhibit tumor invasion and metastasis, relieve ischemia-reperfusion injury, and reduce the immune inflammatory reactions. In order to better understand the pharmacological effects of gadolinium chloride, we reviewed the studies in this field.