局灶性进展为双侧强直-阵挛发作癫痫异常放电神经网络的研究进展
| 作者: |
1史姣姣,
1黄颖,
1李永男
1 哈尔滨医科大学附属第四医院神经内科，哈尔滨 150001 |
| 通讯: |
李永男
Email: yongnanli818@aliyun.com |
| DOI: | 10.3978/j.issn.2095-6959.2021.12.034 |
| 基金: | 哈尔滨医科大学附属第四医院人才扶持项目[HYDSYCXR (202112)]。 |
摘要
癫痫是神经科常见的一种慢性脑部疾病，其对患者的身心健康危害极大，尤其是局灶性进展为双侧强直-阵挛发作(focal to bilateral tonic-clonic seizure，FBTCS)，严重影响患者的生活质量。由于癫痫异常放电传播机制的复杂性和异质性，目前其详细的神经网络传播机制尚不清楚。FBTCS的异常放电神经网络可能有丘脑、基底神经节、胼胝体、脑干、海马和前连合等结构参与。
关键词：
癫痫；局灶性进展为双侧强直-阵挛发作；异常放电；神经网络
Research progress on the neural network of abnormal discharge in focal to bilateral tonic-clonic seizure
CorrespondingAuthor: LI Yongnan Email: yongnanli818@aliyun.com
DOI: 10.3978/j.issn.2095-6959.2021.12.034
Foundation: This work was supported by the Talent Support Project of the Fourth Affiliated Hospital of Harbin Medical University, China [HYDSYCXR (202112)].
Abstract
Epilepsy is a common chronic brain disease in neurology, which is extremely harmful to the patient’s physical and mental health, especially the focal to bilateral tonic-clonic seizure (FBTCS), which seriously affects the quality of patients’ life. Due to the complexity and heterogeneity of the transmission mechanism of abnormal discharge in epilepsy, its detailed transmission mechanism of neural network is still unclear. The neural network of abnormal discharge in FBTCS may involve structures such as thalamus, basal ganglia, corpus callosum, brain stem, hippocampus, anterior commissure, and so on.
Keywords：
epilepsy; focal to bilateral tonic-clonic seizure; abnormal discharge; neural network