胰十二指肠切除术后胰瘘风险评估系统的研究进展
| 作者: |
1张昕宁,
1董烨,
1周毅,
1黄浩,
1张紫昭,
2魏志刚
1 山西医科大学第一临床医学院，太原 030001 2 山西医科大学第一医院普通外科肝胆胰外科，太原 030001 |
| 通讯: |
魏志刚
Email: wzgsyyy@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2022.02.037 |
| 基金: | 山西省重点研发计划项目(201903D321144)。 |
摘要
胰瘘是指胰腺导管系统和另一个上皮表面之间形成的富含胰腺来源酶液体的异常通道。术后胰瘘(postoperative pancreatic fistulas，POPF)会加重患者个人以及社会的卫生经济学负担，可导致严重并发症甚至危及患者生命。精准预测POPF的风险可以优化个体治疗方案，如术后放置引流管、使用生长抑素类似物等。现从对比国内外胰瘘风险评估系统研究进展情况和对常见评估系统的评价以及未来建立胰瘘风险评估系统时应剔除术中出血量、术后病理诊断及患者BMI等存在争议的风险因素来进行改进等方进行综述，为未来进一步优化胰瘘风险评估系统提供借鉴。
关键词：
胰十二指肠切除术；胰瘘；风险评估系统
Research progress of pancreatic fistula risk assessment system after pancreaticoduodenectomy
CorrespondingAuthor: WEI Zhigang Email: wzgsyyy@163.com
DOI: 10.3978/j.issn.2095-6959.2022.02.037
Foundation: This work was supported by the Key R&D Projects in Shanxi Province, China (201903D321144).
Abstract
Pancreatic fistula is an abnormal channel formed between the pancreatic ductal system and the surface of another epithelium, which is rich in pancreas-derived enzyme fluid. Postoperative pancreatic fistula (POPF) can aggravate the burden of health economics on the individual and society, and even endanger the life of the patient when it leads to serious complications. Accurate prediction of POPF risk can optimize individual treatment regimens, such as postoperative drainage tube placement and the use of somatostatin analogs. This paper reviews the research progress of pancreatic fistula risk assessment systems at home and abroad, and comments on common assessment systems, and controversial risk factors such as intraoperative blood loss, postoperative pathological diagnosis, and patient BMI should be excluded when establishing a pancreatic fistula risk assessment system in the future, so as to provide a reference for further optimization of pancreatic fistula risk assessment systems in the future.
Keywords：
pancreaticoduodenectomy; pancreatic fistula; risk assessment system