Objective: To investigate the psychological characteristics and psychological status of patients with benign breast tumors. Methods: A total of 61 patients diagnosed with benign breast tumor in the Breast Department of Zhuhai Hospital(a Traditional Chinese Medicine Hospital in Guangdong) were selected as a case group. Totally 58 patients with breast pain were selected as a breast pain group, and 59 patients with breast hyperplasia were selected as a control group. The Eysenck personality test questionnaire (EPQ) (adult version) was used. The case group and the breast pain group were compared with the control group, and the Eysenck’s personality (E: Extraversion; P: Psychoticism; N: Neuroticism; L: To lie or hide from oneself) was analyzed, respectively. Results: The L value of the case group was higher than that of the control group, and the difference was statistically significant (P<0.05). The scores of E, P and N were close, and the difference was not statistically significant (P>0.05). The E value of the breast pain group was lower than that of the control group, and the difference was statistically significant (P<0.001). N value of the breast pain group was higher than that of the control group, and the difference was statistically significant (P<0.05). P value and L value were close, and the difference was not statistically significant (P>0.05). Conclusion: The Eysenck personality of the patients in the case group was characterized by the tendency to lie and conceal. The patients in the breast pain group had introverted and unstable personality characteristics but did not have the characteristics of concealing. It is suggested that patients with benign breast tumor are more likely to have the psychology of cancer fear than patients with breast pain, thus showing the personality characteristics of lying and concealing.