Objective: To explore the influence of out-of-hospital extended nursing and pulmonary rehabilitation training on the life quality and recovery of chronic obstructive pulmonary disease (COPD) in stable period, and to provide theoretical basis for clinical practice. Methods: A total of 80 patients with COPD in stable period who were discharged from our hospital from October 2017 to October 2019 were selected for the study. The random number table method was used to divide the patients into an observation group and a control group, each with 40 cases. Patients in the control group received routine nursing intervention, and patients in the observation group received extended nursing combined with pulmonary rehabilitation training. The changes of lung function, quality of life, self-efficacy, and daily life activity of patients in the two groups on the day of discharge and 60 days after intervention were observed, and nursing satisfaction was counted. Results: On the day of discharge, the lung function, life quality, self-efficacy, and ability of daily living activities in two groups of patients were compared, without a statistically significant difference (P>0.05). After 60 days of intervention, the levels of FEV1, FVC, FEV1/FVC [(0.89±0.09) L, (1.78±0.27) L, (63.75±6.17)%] in the observation group were significantly higher than those in the control group [(0.83±0.08) L, (1.63±0.29) L, (54.21±6.15)%], and the difference was statistically significant (P<0.05). The scores of physical function, emotional function, mental health, and physical pain in the observation group [(73.48±6.23) points, (76.25±7.57) points, (78.31±6.37) points, (80.97±5.10) points] were significantly higher than those in the control group [(65.79±6.22) points, (65.38±7.52) points, (70.92±6.34) points, (74.55±5.09) points], and the difference was statistically significant (P<0.05). The self-efficacy and daily living activity scores of patients in the observation group [(33.43±2.16) points, (72.31±6.11) points] were significantly higher than those in the control group [(28.71±2.17) points, (65.92±6.12) points], and the difference was statistically significant (P<0.05). The nursing satisfaction of the observation group was 97.50%, which was significantly higher than that of the control group (82.50%), the difference was statistically significant (P<0.05). Conclusion: Out-of-hospital extended nursing and pulmonary rehabilitation training can effectively improve the life quality of patients with COPD in stable period, promote the rapid recovery of patients’ pulmonary function, improve patients’ self-efficacy and ability of daily life activities, and increase the degree of satisfaction, which are worthy of clinical promotion.