卵圆孔未闭与隐源性卒中及其危险因素之间关系的研究进展
| 作者: |
1李艳,
1廖晓阳
1 四川大学华西医院特需医疗中心/全科医学病房，成都 610041 |
| 通讯: |
廖晓阳
Email: 605327704@qq.com |
| DOI: | 10.3978/j.issn.2095-6959.2021.05.034 |
| 基金: | 四川大学华西医院临床研究孵化项目(2018HXFH005)；四川省科技计划项目(2019JDR0277，2019YFS0013)。 |
摘要
隐源性卒中占所有缺血性卒中的30%~40%，随着影像学技术的发展，其发病率仍居高不下。虽然多种危险因素(既往卒中、高血压、静脉血栓病史、高脂血症、高同型半胱氨酸血症等)被提出，高风险的卵圆孔未闭却是近年来才被认识的隐源性卒中的危险因素。越来越多的研究表明卵圆孔未闭和隐源性卒中密切相关。对于合适的患者而言，卵圆孔未闭封堵术可明显降低隐源性卒中患者的卒中复发风险。
关键词：
隐源性卒中；卵圆孔未闭；危险因素
Research progress in the relationship between patent foramen ovale and cryptogenic stroke and its risk factors
CorrespondingAuthor: LIAO Xiaoyang Email: 605327704@qq.com
DOI: 10.3978/j.issn.2095-6959.2021.05.034
Foundation: This work was supported by Clinical Research Incubation Program at Hwaseo Hospital, Sichuan University (2018HXFH005), and Sichuan Science and Technology Program (2019JDR0277, 2019YFS0013), China.
Abstract
Cryptogenic stroke accounts for about 30%–40% of all ischemic strokes. With the development of imaging technology, its incidence remains high. Although several risk factors (previous stroke, hypertension, history of venous thrombosis, hyperlipidemia, hyperhomocysteinemia, etc.) have been proposed, the high-risk patent foramen ovalis has been recognized as a risk factor for cryptogenic stroke in recent years. More and more studies have shown that the patent foramen ovale is closely related to cryptogenic stroke. With an appropriate patient selection, the patent foramen ovale closure can significantly reduce the risk of stroke recurrence in patients with cryptic stroke.
Keywords：
cryptogenic stroke; patent foramen ovale; risk factors