文章摘要

集束化营养护理对胃癌新辅助化疗患者营养指标及免疫水平的影响

作者: 1陈婷婷, 2李彬彬, 1郝艳娇
1 辽宁省肿瘤医院消化内科,沈阳 110042
2 抚顺市第二医院高压氧治疗室,辽宁 抚顺 113001
通讯: 郝艳娇 Email: 370499323@qq.com
DOI: 10.3978/j.issn.2095-6959.2021.03.022

摘要

目的:探讨集束化营养护理对胃癌新辅助化疗患者营养指标及免疫水平的影响。方法:选取辽宁省肿瘤医院2019年1月至6月收治的40例胃癌化疗的患者为对照组,采用常规营养护理;选取辽宁省肿瘤医院2019年7月至12月收治的42例胃癌化疗的患者为观察组,采用集束化营养护理。比较两组化疗3个周期后的营养指标、免疫水平的变化。结果:观察组化疗3个周期后的白蛋白(albumin,ALB),血红蛋白(hemoglobin,Hb)高于对照组,体重指数(body mass index,BMI)大于对照组,差异有统计学意义(P<0.05)。观察组化疗3个周期后的营养风险低于对照组,差异有统计学意义(P<0.05)。观察组化疗3个疗程后CD4+,CD4+/CD8+高于对照组,CD8+低于对照组,差异有统计学意义(P<0.05)。结论:集束化营养护理能够减轻胃癌新辅助化疗患者的营养风险,改善化疗期间的营养指标,提升免疫功能。
关键词: 集束化营养护理;胃癌;新辅助化疗;营养指标;免疫水平

Effect of cluster nutrition care on nutritional indexes and immune level in gastric cancer patients with neoadjuvant chemotherapy

Authors: 1CHEN Tingting, 2LI Binbin, 1HAO Yanjiao
1 Department of Gastroenterology, Liaoning Cancer Hospital, Shengyang 110042, China
2 Hyperbaric Oxygen Treatment Room, Fushun Second Hospital, Fushun Liaoning 113001, China

CorrespondingAuthor: HAO Yanjiao Email: 370499323@qq.com

Abstract

Objective: To explore the effect of cluster nutrition care on nutritional indexes and immune level in patients with neoadjuvant chemotherapy for gastric cancer. Methods: A total of 40 patients with neoadjuvant chemotherapy for gastric cancer in Liaoning Cancer Hospital from January to June 2019 were included as a control group that received routine nutritional care. Totally 42 patients with neoadjuvant chemotherapy for gastric cancer in Liaoning Cancer Hospital from July to December 2019 were included as an observation group that received cluster nutrition care. The nutritional indexes and immune levels of the 2 groups were compared after 3 courses of chemotherapy. Results: Hemoglobin (Hb) and albumin (ALB) of the observation group after 3 courses of chemotherapy were higher than those of the control group, and body mass index (BMI) was higher than that of the control group as well, and the difference was statistically significant (P<0.05). The nutritional risk of the observation group after 3 courses of chemotherapy was lower than that of the control group, and the difference was statistically significant (P<0.05). After 3 courses of chemotherapy, CD4+ and CD4+/CD8+ in the observation group were higher than those in the control group, and CD8+ in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Cluster nutrition care can reduce the nutritional risk of patients with neoadjuvant chemotherapy for gastric cancer, improve the nutritional indicators during chemotherapy, and immune function.
Keywords: cluster nutrition care; gastric cancer; neoadjuvant chemotherapy; nutritional indicators; immune level