急性胆管炎中血清标志物的研究现状
| 作者: |
1白晓东,
1李之拓,
1靳亚杰,
1曹献启,
1武凯,
1孙海军
1 哈尔滨医科大学附属第一医院微创胆道外科，哈尔滨 150001 |
| 通讯: |
孙海军
Email: 15945777708@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2021.02.028 |
摘要
急性胆管炎是一种威胁生命的胆道细菌感染，能否及早诊断、评估疾病严重程度直接关系到患者的治疗效果与预后。长期以来对血清中标志物的研究较多，如降钙素原(procalcitonin，PCT)、血清糖类抗原CA19-9(carbohydrate antigen 19-9)、血清前白蛋白(prealbumin，PA)、高迁移率蛋白-1(high mobility group box 1，HMGB1)，这些标志物与急性胆管炎病理生理均有密切联系。
关键词：
急性胆管炎；降钙素原；血清糖类抗原CA19-9；前白蛋白；高迁移率蛋白-1
Research status of serum markers in acute cholangitis
CorrespondingAuthor: SUN Haijun Email: 15945777708@163.com
DOI: 10.3978/j.issn.2095-6959.2021.02.028
Abstract
Aute cholangitis is a life-threatening bacterial infection of the bile duct and the early diagnosis and evaluation of the severity of cholangitis patients are therefore directly related to the treatment response and prognosis. For a long time, there are numbers of studies on serum markers, such as procalcitonin (PCT), serum carbohydrate antigen 19-9 (CA19-9), prealbumin (PA) and high mobility group box 1 (HMGB1). These markers are closely associated to the pathophysiology of acute cholangitis. This review summarizes the research status of the above markers.
Keywords：
acute cholangitis; procalcitonin; carbohydrate antigen 19-9; prealbumin; high mobility group box 1