Objective: To explore the clinical value and comparative study of contrast-enhanced ultrasonography (CEUS) and contrast-enhanced MRI (CE-MRI) in postoperative efficacy evaluation of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE), in order to provide the basis for the choice of imaging methods for patients with HCC in the review after TACE treatment. Methods: From Jan. 2018 to Dec. 2018, 33 patients with HCC (a total of 83 lesions) that underwent TACE one month ago in our hospital intervention department received CE-MRI, CEUS and digital subtraction angiography (DSA) within a week. If the residual or recurrent lesions were found, TACE would be performed again. Kappa test and McNemar test were performed on the DSA results, and compared the sensitivity, specificity, accuracy and consistency of the three examinations. Results: The diagnostic accuracy of CEUS and CE-MRI was 91.6% and 100%, respectively. The diagnostic accuracy of CE-MRI was better than that of CEUS, and the difference was statistically significant. The results of CEUS were consistent with CE-MRI (Kappa =0.794). The sensitivity and specificity of CE-MRI were both 100%, and CEUS were 88.9% and 100%, respectively. In the lesions >3 cm, the consistency between CEUS and CE-MRI was strong (Kappa =0.891), and the accuracy, sensitivity and specificity of CEUS were 96.1%, 95.0% and 100%, respectively. In the lesions ≤3 cm, the consistency between CEUS and CE-MRI was general (Kappa =0.669), and the accuracy, sensitivity and specificity of CEUS were 84.4%, 78.3% and 100%, respectively. Conclusion: CEUS, CE-MRI and gold standard DSA have the same diagnosis consistency after TACE. CEUS can be used as an alternative imaging method for short-term TACE reexamination of primary liver cancer.