罕见视神经脊髓炎合并系统性红斑狼疮1例并文献复习
| 作者: |
1张小花,
1彭立,
2李香营,
1谢青
1 中南大学湘雅医学院附属海口医院眼科，海口 570208 2 中南大学湘雅医学院附属海口医院放射科，海口 570208 |
| 通讯: |
谢青
Email: opht_xq@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2021.01.038 |
摘要
报告1例罕见病变累及8个脊髓节段的视神经脊髓炎合并系统性红斑狼疮的病例，分析其发病现状和最新进展，并复习相关文献。1名48岁女性，因“左眼视力下降2个月，双下肢麻痹无力伴胸痛3 d”入院，眼底血管造影提示左眼球后视神经炎，脊髓MRI提示C5~T7脊髓炎，经综合治疗后病情好转。视神经脊髓炎合并系统性红斑狼疮发病非常罕见，其发病机制与广泛的自体免疫性疾病有关，及时正确诊断和治疗对患者的预后起至关重要的作用。
关键词：
视神经脊髓炎；系统性红斑狼疮；视神经脊髓炎抗体
Neuromyelitis optica complicated with systemic lupus erythematosus: A case report and literature review
CorrespondingAuthor: XIE Qing Email: opht_xq@163.com
DOI: 10.3978/j.issn.2095-6959.2021.01.038
Abstract
A rare case of neuromyelitis optica (NMO) involving eight spinal segments with lupus erythematosus (SLE) was reported with the symptoms and progress analyzed and the related literature reviewed. A 48-year-old female presented with decreased vision in her left eye for 2 months, paralysis and weakness of both lower limbs with chest pain for 3 days was admitted to the hospital. Fundus angiography showed optic neuritis in the left eye. Spinal MRI showed acute myelitis of C5–T7. The lesions improved significantly after therapy. NMO combined with SLE is rare and its pathogenesis is associated with the wide autoimmune disease. Timely and accurate diagnosis and treatment is critical for patients to achieve a favorable prognosis.
Keywords：
neuromyelitis optica; systemic lupus erythematosus; neuromyelitis optica antibody