革命性的发现：氧气感知——2019年诺贝尔生理学或医学奖简介
| 作者: |
1谢文清,
1何苗,
1李宇晟
1 中南大学湘雅医院骨科，长沙 410011 |
| 通讯: |
李宇晟
Email: liyusheng@csu.edu.cn |
| DOI: | 10.3978/j.issn.2095-6959.2020.07.048 |
| 基金: | 国家自然科学基金(81874030)。 |
摘要
2019年诺贝尔生理学或医学奖揭晓，威廉·凯林(William G. Kaelin Jr)、彼得·拉特克利夫(Sir Peter J. Ratcliffe)和格雷格·塞门扎(Gregg L. Semenza)获得这一奖项，以表彰他们在理解人体和大多数动物细胞感知和适应氧气变化机制中的贡献。
关键词：
诺贝尔生理学或医学奖；缺氧诱导因子；VHL基因
Revolutionary discovery: oxygen sensing—introduction of Nobel Prize in Physiology or Medicine 2019
CorrespondingAuthor: LI Yusheng Email: liyusheng@csu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2020.07.048
Foundation: This work was supported by the National Natural Science Foundation of China (81874030).
Abstract
The 2019 Nobel Prize in Physiology or Medicine was awarded to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza for their contributions to understand the mechanisms of human and most animal cells’ perception and adaptation to oxygen changes.
Keywords：
Nobel Prize in Physiology or Medicine; hypoxia-inducible factors; Von Hippel-Lindau gene