阿司匹林抗肝癌的作用机制及临床研究进展
| 作者: |
1费锐,
1刘磊,
1刘伟
1 三峡大学第一临床医学院，三峡大学消化疾病研究所，宜昌市中心人民医院消化内科，湖北 宜昌 443000 |
| 通讯: |
刘伟
Email: liuwei@ctgu.edu.cn |
| DOI: | 10.3978/j.issn.2095-6959.2020.06.040 |
| 基金: | 国家自然科学基金(NO.31600134)。 |
摘要
目前肝癌是我国和全球发病率及病死率都很高的恶性肿瘤之一，且治疗效果差，给患者带来了沉重的经济负担。阿司匹林作为一种古老的药物，对包括肿瘤在内的许多疾病都有疗效。在临床回顾、基础研究中，又发现了其对肝癌有确切的预防和治疗作用。几十年来，关于阿司匹林抗肝癌的机制逐渐被揭示。
关键词：
肝癌；阿司匹林；作用机制
Mechanism and clinical research progress of aspirin against liver cancer
CorrespondingAuthor: LIU Wei Email: liuwei@ctgu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2020.06.040
Foundation: This work was supported by National Natural Science Foundation of China (31600134).
Abstract
Liver cancer is one of the malignant tumors with high morbidity and mortality in the world and China with poor treatment effect, which brings a heavy economic burden to patients. As an ancient drug, aspirin has been found to have many miraculous therapeutic effects against many diseases including tumors. In clinical review and basic research, it has been found to have a definite preventive and therapeutic effect on liver cancer. For decades, mechanism of anti-hepatocarcinoma by aspirin has been gradually revealed.
Keywords：
liver cancer; aspirin; mechanism