MiR-17-92簇的研究进展
| 作者: |
1张洁,
1陈金安,
1孙新娟,
1董磊磊,
1王爱萍
1 东部战区空军医院内分泌科，南京 210002 |
| 通讯: |
王爱萍
Email: wap454hospital@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2020.06.035 |
| 基金: | 国家科学自然基金(81770810)。 |
摘要
MiR-17-92是一个高度保守的基因簇，该基因簇主要有6个成员，包括miR-17，miR-18a，miR-19a，miR-20a，miR-19b-1和miR-92a。这些基因通过调控靶基因参与肿瘤的发生、发展，参与一些细胞的免疫反应，并在内分泌系统中发挥一定的作用。
关键词：
miR-17-92簇；肿瘤；免疫；内分泌系统
Research progress of miR-17-92 cluster
CorrespondingAuthor: WANG Aiping Email: wap454hospital@163.com
DOI: 10.3978/j.issn.2095-6959.2020.06.035
Foundation: This work was supported by the National Natural Science Foundation of China (81770810).
Abstract
MiR-17-92 is a highly conserved gene cluster with six members, including miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1, and miR-92a. These genes are involved in the development of tumors, which participate in some immune responses of cells, and also play a role in endocrine system.
Keywords：
miR-17-92cluster; tumor; immunity; endocrine system