Objective: To study the effect of fine nursing in the treatment of children with lobar pneumonia by fiberoptic bronchoscopy, the purpose is to provide reference for clinical nursing. Methods: Sixty cases children with lobar pneumonia admitted to Wanbei Coal Power Group General Hospital from August 2018 to September 2019 were selected conduct research, through different treatment time, 30 children from August 2018 to April 2019 as control group, 30 children from May 2019 to September 2019 as observation group. were treated with fiberoptic bronchoscope. The control group received routine nursing during the treatment, while the observation group received fine nursing on the basis of the control group. After nursing 7 days, the clinical efficacy, disappearance time of clinical symptoms, antibiotic use time, hospitalization time, children family satisfaction and complications were compared between the two groups. Results: After nursing 7 days, the total effective rate was the higher of the observation group and the control group, 96.67% and 80.0% respectively. The difference was statistically significant (P<0.05); the disappearance time of high fever cough, pulmonary rales, antibiotic use time and hospitalization time in the control group was much longer than the observation group, and the difference were statistically significant (P<0.05); the children family satisfaction of the control group was obviously not as high as the observation group and the difference were statistically significant (P<0.05); there were no serious complications in two groups. Conclusion: Fine nursing is well for children with lobar pneumonia by fiberoptic bronchoscopy, and it’s helpful to shorten the recovery time of symptoms and hospitalization time, improve the clinical efficacy and the children family satisfaction, it’s worth popularizing.