急性横贯性脊髓炎预后影响因素的研究进展
| 作者: |
1杨甫兰,
2陈应柱,
2刘佩佩,
2朱艳
1 大连医科大学扬州临床医学院，江苏 扬州 225001 2 扬州大学附属苏北人民医院神经内科，江苏 扬州 225001 |
| 通讯: |
朱艳
Email: 18840827708@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2020.03.032 |
| 基金: | 江苏省“六大人才”高峰培养资助项目(WSW-246)；江苏省“333工程”专项经费资助项目(BRA2015187)；扬州市“十三五”科教强卫专项经费(LJRC20187)；江苏省苏北人民医院省级重点专科学科带头人专项经费。 |
摘要
急性横贯性脊髓炎(acute transverse myelitis，ATM)病因不明，目前多认为与感染后引起的自身免疫反应相关，部分患者于疫苗接种后发病。脊髓炎可引起脊髓水肿变软，导致病变平面以下运动、感觉等功能障碍。ATM患者的预后不一，从完全康复到致残，甚至死亡。大约1/3的患者恢复良好，1/3的患者恢复尚可，剩下1/3的患者病情很少或基本没有好转。ATM的预后取决于病变的严重程度及合并症的情况，但更精确的预测是困难的。
关键词：
横贯性脊髓炎；预后；预测因子
Recent advances in prognostic factors of acute transverse myelitis
CorrespondingAuthor: ZHU Yan Email: 18840827708@163.com
DOI: 10.3978/j.issn.2095-6959.2020.03.032
Foundation: This work was supported by the Jiangsu Provincial “Six Talents” Peak Training Funding Project (WSW-246); Jiangsu Provincial 333 Project Special Funding Project (BRA2015187); Yangzhou City’s “13th Five-Year” Science and Education Strengthening Special Funding (LJRC20187); Special Fund for the Provincial Key Special Sciences Leader of Northern Jiangsu People’s Hospital, China.
Abstract
The etiology of acute transverse myelitis (ATM) is still unclear, and it is currently thought to be related with autoimmune responses caused by infection. Spinal cord edema caused by ATM can leads to dysfunction below the lesion plane. The prognosis of patients with ATM varies from complete rehabilitation to disabling neurological deficits and even death. About 1/3 of the patients had full recovery, 1/3 of the patients had fair recovery, and the remaining 1/3 had little or no recovery. Prediction of ATM prognosis could be difficult.
Keywords：
transverse myelitis; prognosis; predictor