Objective: To identify risk factors of abnormal computerized tomography in children with mild traumatic brain injury and clarify clinical factors using computerized tomography. Methods: Between Jan 2014 and Dec 2016, we retrospectively enrolled 175 children that were <15 years old with mild TBI. Data was recorded including gender, age, GCS score on admission, causes of head injury, first CT time, loss of consciousness, vomiting, and seizure. Of them, 103 of male, 72 female, and the age was (8.2±3.5) years. Fall (n=99) were the leading mechanism of injury, followed by traffic accidents (n=67). Based on initial CT findings, they were dichotomized into either a normal CT group or an abnormal CT group. Besides, clinical data were reviewed for comparison. Multivariate logistic regression analysis was also applied to identify risk factors of abnormal CT. Results: Univariate analysis showed between-group differences were significant in gender (P=0.001), age (P=0.008) and vomiting (P=0.019). Multivariate logistic regression analysis identified age (OR=4.267, 95%CI 1.518–11.991, P=0.006) and vomiting (OR=3.05, 95%CI 1.356–6.877, P=0.007) as independent risk factors of abnormal CT in children with mild traumatic brain injury. Conclusion: Age ≤6 years old and vomiting are associated with abnormal CT. These factors should be considered when making decisions on CT of children with mild TBI.