急性纤维素性机化性肺炎的研究进展
| 作者: |
1文誉,
2李爱民
1 山西医科大学第一临床医学院，太原 030001 2 山西医科大学第一医院呼吸与危重症医学科，太原 030001 |
| 通讯: |
李爱民
Email: dcliaim@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2019.08.030 |
摘要
急性纤维素性机化性肺炎(acute fibrinous and organizing pneumonia，AFOP)是一种具有急性、亚急性临床表现，组织病理学表现以肺泡腔内“均质嗜酸性纤维素球”改变为显著特征的一种与急性肺损伤相关的不同于典型弥漫性肺泡损伤(diffuse alveolar damage，DAD)、隐源性机化性肺炎(cryptogenic organizing pneumonia，COP)、嗜酸性粒细胞肺炎(eosinophil pneumonia，EP)的特发性间质性肺炎的罕见的组织病理学类型。由于其临床表现、胸部CT影像学无特异性，确诊需依据肺活检，因此临床上易误诊及漏诊。
关键词：
急性纤维素性机化性肺炎；组织病理；治疗
Research progress on acute fibrinous and organizing pneumonia
CorrespondingAuthor: LI Aimin Email: dcliaim@163.com
DOI: 10.3978/j.issn.2095-6959.2019.08.030
Abstract
Acute fibrinous and organizing pneumonia (AFOP) is a rare histologic pattern of lung injury with an acute/subacute clinical presentation, which is characterized histologically by homogeneous eosinophil fibrin balls within the alveoli, as well as inflammatory cells in the interstitium, and does not meet the criteria for either diffuse alveolar damage (DAD), cryptogenic organizing pneumonia (COP) or eosinophil pneumonia (EP). Due to its non-specific clinical manifestations and images, the diagnosis should be based on lung biopsy histology, so it is easy to miss diagnosis and misdiagnosis.
Keywords：
acute fibrinous organic pneumonia; histopathology; therapy