Objective: To explore the risk factors of incontinence-associated dermatitis (IAD) among hospitalized adult patients. Methods: The Meta-analysis method was used to search the electronic databases, and the relevant literature on IAD in adult hospitalized patients was collected. After the literature quality evaluation, Revman 5.3 software and Stata 11.0 software were used for data analysis. Results: Fourteen studies, eleven Chinese and three English, were recruited, involving 2 371 patients. The results of Meta-analysis showed that fecal incontinence, double incontinence, character of stools, fever, diabetes, antibiotics, corticosteroids, tube feeding, level of albumin, Braden scores and PAT scores were the risk factors of IAD(all P<0.05). Conclusion: The risk factors of incontinence-associated dermatitis in adults include fecal incontinence, double incontinence, character of stools, fever, diabetes, antibiotics, corticosteroids, tube feeding, level of albumin, Braden scores and PAT scores. Medical staff should pay attention to these risk factors in clinical work, and actively carry out early nursing intervention to reduce the incidence of IAD in hospitalized patients and reduce the physical and psychological pain of patients.