文章摘要

粪便菌群移植治疗溃疡性结肠炎的研究进展

作者: 1薛书锦, 2周建博, 3郭子皓
1 首都医科大学附属北京同仁医院教育处，北京 100000
2 首都医科大学附属北京同仁医院内分泌科，北京 100000
3 首都医科大学附属北京同仁医院消化内科，北京 100000
通讯: 薛书锦 Email: alimiyaghost@163.com
DOI: 10.3978/j.issn.2095-6959.2019.08.033

摘要

肠道菌群改变对多种胃肠道和非胃肠道疾病的治疗已成为时下研究热点。溃疡性结肠炎患者普遍存在肠道菌群改变现象，通过调整和恢复肠道菌群治疗溃疡性结肠炎的临床试验正逐步开展。粪便菌群移植(fecal microbiota transplantation，FMT)治疗旨在通过健康人粪便移植物重建肠道菌群，恢复肠道微生态，从而达到治疗目的。
关键词： 肠道菌群；溃疡性结肠炎；粪便菌群移植治疗

Research progress of fecal microbiota transplantation in the treatment of ulcerative colitis

Authors: 1XUE Shujin, 2ZHOU Jianbo, 3GUO Zihao
1 Department of Education, Beijing Tongren Hospital, Capital Medical University, Beijing 100000, China
2 Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing 100000, China
3 Department of Gastroenterology, Beijing Tongren Hospital, Capital Medical University, Beijing 100000, China

CorrespondingAuthor: XUE Shujin Email: alimiyaghost@163.com

DOI: 10.3978/j.issn.2095-6959.2019.08.033

Abstract

Modification of intestinal microbiome for the treatment of gastrointestinal and non-gastrointestinal diseases has been a current research hotspot. Changes in intestinal microbiota are common in patients with ulcerative colitis and clinical trials were conducted for treating ulcerative colitis by adjusting and restoring intestinal microbiota. Fecal microbiota transplantation (FMT) aims to rebuild intestinal microbiota and restore intestinal micro-ecology through fecal transplant.
Keywords： intestinal microbiome; ulcerative colitis; fecal microbiota transplantation

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