文章摘要

放射性肺损伤及康复研究进展

作者: 1夏露露, 2陈伟, 2高民, 2,3张明, 3李瑾, 4陈猛
1 徐州医科大学医学技术学院，江苏 徐州 221004
2 徐州医科大学徐州临床学院康复医学科，江苏 徐州 221009
3 徐州医科大学附属徐州康复医院康复医学科，江苏 徐州 221003
4 徐州市中心医院放疗科，江苏 徐州 221009
通讯: 陈伟 Email: chenwei2339@163.com
DOI: 10.3978/j.issn.2095-6959.2019.06.032
基金: 江苏省青年医学人才基金 (QNRC2016376)；徐州市医学青年后备人才工程 (2016015)。

摘要

放射性肺损伤是胸部肿瘤放射治疗中较常见的并发症，是放疗剂量的主要限制因素，降低了肿瘤局部控制率，严重影响患者生活质量和远期生存率。本文主要从放射性肺损伤的发病机制、病理改变、预测指标以及康复医学相关干预等方面的研究进展加以综述。
关键词： 放射性肺损伤；细胞因子；预测指标；康复干预

Research progress in radiation-induced lung injury and rehabilitation

Authors: 1XIA Lulu, 2CHEN Wei, 2GAO Min, 2,3ZHANG Ming, 3LI Jin, 4CHEN Meng
1 Academy of Medical Technology, Xuzhou Medical University, Xuzhou Jiangsu 221004, China
2 Department of Rehabilitation, Xuzhou Clinical Academy of Xuzhou Medical University, Xuzhou Jiangsu 221009, China
3 Department of Rehabilitation, Xuzhou Rehabilitation Hospital, Xuzhou Medical University, Xuzhou Jiangsu 221003, China
4 Department of Radiotherapy, Xuzhou Central Hospital, Xuzhou Jiangsu 221009, China

CorrespondingAuthor: CHEN Wei Email: chenwei2339@163.com

DOI: 10.3978/j.issn.2095-6959.2019.06.032

Foundation: This work was supported by the Jiangsu Provincial Medical Youth Talent (ONRC2016376) and Xuzhou Medical Young Talents Project (2016015), China.

Abstract

Radiation-induced lung injury is a common complication in radiotherapy of thoracic tumors, which is the main limiting factor of radiation dose. It reduces the local control rate of tumor and seriously affects the quality of life and long-term survival rate of patients. This paper mainly reviews the research progress of its pathogenesis, pathological changes, predictors and rehabilitation medicine-related interventions.
Keywords： radiation-induced lung injury; cytokines; predictors; rehabilitation medicine-related interventions

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