Objective: To analyze the epidemiological status of abnormal indicators of main chronic diseases in public institutions in Baoan District Province, and explore the abnormal detection and distribution characteristics of chronic diseases and related factors. Methods: A total of 12 925 cases performing a physical examination in 2014 in the Baoan District authorities and institutions were enrolled in the study, and a unified examination program was obtained. The fasting venous blood in all staff was used to measure the level of TC, TG, LDL-C, blood sugar, uric acid; the height, weight, systolic blood pressure and diastolic blood pressure were also measured in the unified and standard method. Results: The health examination results showed that the abnormal index detection rate in the Baoan District institutions was 71.7%, of which 863 people suffer from high blood sugar (6.7%), 2 600 people with high uric acid (20.12%), 4 292 were abnormal body weight (33.2%); 6 915 patients with hyperlipidemia (53.5%) and 1 554 patients with hypertension (12%). Conclusion: The main chronic disease indicators of physical examination population in Baoan District organs and institutions are characterized by high abnormal detection rate and obvious younger trend. Relevant departments should pay attention to and take effective measures to formulate health promotion plan.