软骨下骨在骨关节炎自然病程中作用的研究进展
| 作者: |
1谭向前,
1刘学勇
1 中国医科大学附属盛京医院脊柱关节外科，沈阳 110000 |
| 通讯: |
谭向前
Email: 1113098488@qq.com |
| DOI: | 10.3978/j.issn.2095-6959.2018.01.030 |
摘要
骨关节炎(osteoarthritis，OA)是人类常见的骨关节疾病之一，好发于中老年人群，严重影响中老年人的生活质量。近几年对OA发生发展的研究取得了一定进展。既往研究认为软骨原发退变和继发性的骨质增生是OA基本病理变化，但目前有研究认为软骨下骨早期直接参与了OA的发生过程。
关键词：
骨关节炎；自然病程；软骨下骨
Research progress of subchondral bone in the natural course of osteoarthritis
CorrespondingAuthor: TAN Xiangqian Email: 1113098488@qq.com
DOI: 10.3978/j.issn.2095-6959.2018.01.030
Abstract
Osteoarthritis, one of the human bone joint diseases, usually occurs in the elderly population and seriously influences the quality of life in elderly people. A large number of studies on the occurrence and development of osteoarthritis in recent years has made some progress. Previous researches deem that the cartilage primary degeneration and bone secondary hyperplasia are the basic pathological changes of osteoarthritis; however, recent studies show that the subchondral bone is directly involved in occurrence and development of osteoarthritis.
Keywords：
osteoarthritis; natural course; subchondral bone