Objective: To investigate the current situation and influencing factors of nurses’ time management disposition in grade three first class hospitals in Zhengzhou. Methods: A questionnaire survey was conducted among 525 nurses from 6 grade A tertiary hospitals in Zhengzhou by using the method of staged sampling and using the time management disposition scale for nurses. Results: The scores of nurses’ time management disposition were 3.58±0.57 at middle level, which were lower than that of employees. The sense of time efficacy and sense of time monitoring was higher than that of nurses in Beijing and Shenzhen. The sense of time value and sense of time monitoring was lower than that of College counselors. The promotion of educational background, job satisfaction and participation in continuing education programs were the factors influencing nurses’ time management disposition. Conclusion: Providing more opportunities to participate in continuing education programs and encouraging nurses to continue to enhance education, creating a relaxed working environment can improve the ability of time management and improve the work efficiency of nurses to meet the needs of clinical work objective.