胃弥漫性大B细胞淋巴瘤易误诊为胃癌1例临床病理分析
| 作者: |
1张俊,
2魏建国,
1许春伟,
1吴永芳,
1王怀涛,
1王海艳,
1张博,
1邵云,
1李晓兵
1 军事医学科学院附属医院病理科，北京 100071 2 浙江省绍兴市人民医院病理科，浙江 绍兴 312000 |
| 通讯: |
吴永芳
Email: wwyff7950385@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2015.07.042 |
摘要
目的：探讨胃弥漫性大B细胞淋巴瘤的临床及病理特点，减少误诊误治。方法：对所获军事医学科学院附属医院病理科诊断为胃弥漫性大B细胞淋巴瘤1例病例的临床及病理资料进行回顾性分析。结果：本例胃镜检查发现胃窦见直径约6.0 cm以前壁和大弯侧为主、浸润生长的、周边不规则的溃疡型隆起，中央污秽苔，并见紫蓝色血痂，诊断为胃体窦交界部溃疡型癌。后经我院活检病理及免疫组织化学结果证实为非霍奇金淋巴瘤，类型考虑为弥漫性大B细胞淋巴瘤。结论：胃弥漫性大B细胞淋巴瘤临床及病理类型少见，易误诊为低分化癌，应加强对胃淋巴瘤的临床及病理学特征的认识并仔细分析病情，以避免或减少误诊误治。
关键词：
胃
弥漫性大B细胞淋巴瘤
低分化癌
误诊
One case of clinicopathological analyses of gastric diffuse large B cell lymphoma to misdiagnosis as gastric cancer
CorrespondingAuthor: WU Yongfang Email: wwyff7950385@163.com
DOI: 10.3978/j.issn.2095-6959.2015.07.042
Abstract
Objective: Though investigating the clinical and pathological features of gastric diffuse large B cell lymphoma to reduce misdiagnosis and mistreatment. Methods: Clinical and pathological data was retrospectively analyzed in one case of gastric diffuse large B cell lymphoma, which was diagnosed by Affiliated Hospital of Military Medical Sciences. Results: The endoscope found that this lesion had an invasion surrounding irregular ulcer type uplift of a diameter about 6.0 cm in anterior wall and the greater curvature of gastric antrum, with central filthy fur, and it also had a violet blue blood scab. It was diagnosed as gastric antrum junction ulcerative carcinoma. After that, the biopsy and immunohistochemical results confirmed non-Hodgkin’s lymphoma as the type, and it was considered as diffuse large B cell lymphoma. Conclusion: Clinical and pathological type of gastric diffuse large B cell lymphoma is rare, which is often misdiagnosed as poorly differentiated carcinoma cancer. We should strengthen the clinical and pathological features of gastric diffuse large B cell lymphoma awareness and careful analysis of the condition, in order to avoid or reduce misdiagnosis and mistreatment.