文章摘要

细胞外基质蛋白Asporin的研究进展

作者: 1王丽丽, 1汪莉, 1吴焕文, 1梁智勇, 1刘彤华
1 北京协和医院病理科，北京 100730
通讯: 梁智勇 Email: liangzhiyong1220@yahoo.com
刘彤华 Email: Tonghua_liu@163.com
DOI: 10.3978/j.issn.2095-6959.2016.02.015
基金: 卫生行业科研专项, 201402001 国家自然科学基金项目, 31471366 北京协和医院青年基金项目, A107000 教育部博士点基金, 81150027

摘要

近年来，随着对人类疾病认识的加深，细胞外基质(extracellular matrix，ECM)蛋白引起了学者们的广泛关注。Asporin是近年来在ECM中新发现的一种富含亮氨酸的小分子蛋白多糖(small leucine rich proteoglycan，SLRP)。目前很多研究表明，Asporin在人类多种疾病(炎症性疾病、退化性疾病和肿瘤)的发生、发展中发挥着重要的作用。本文就Asporin在人类疾病中的研究现状作一综述。
关键词： Asporin 小分子蛋白多糖 炎症 肿瘤

A review of Asporin and human disease

Authors: 1WANG Lili, 1WANG Li, 1WU Huanwen, 1LIANG Zhiyong, 1LIU Tonghua
1 Department of Pathology, Peking Union Medical College Hospital, Beijing 100730, China

CorrespondingAuthor: LIANG Zhiyong Email: liangzhiyong1220@yahoo.com

DOI: 10.3978/j.issn.2095-6959.2016.02.015

Abstract

Recently, increasing researches revealed that extracellular matrix (ECM) proteins play important roles in human disease development. Asporin is one of the components in ECM, which belongs to the family of small leucine rich proteoglycan (SLRP). It has been revealed that Asporin is associated with various human diseases. Therefore, we perform an overview of the researches between Asporin and human disease.

文章选项

下载引文

分享