乳腺原发性血管肉瘤病理特征1例并文献复习
| 作者: |
1黄婷,
1周仁钰,
1陆元志
1 暨南大学附属第一医院临床病理科，广州 510630 |
| 通讯: |
陆元志
Email: Yuanzhi.lu@jnu.edu.cn |
| DOI: | 10.3978/j.issn.2095-6959.2021.04.038 |
| 基金: | 国家自然科学基金(81572606)。 |
摘要
乳腺原发性血管肉瘤(primary breast angiosarcoma，PBA)是乳腺罕见的恶性肿瘤，其病理形态多样，常表现为异常增生的血管样结构。由于该病发病机制尚不明确，无特征临床表现，组织学变化大，术前活检及术中冰冻诊断困难。本文结合1例PBA病理诊断探讨该肿瘤的临床病理特点、可能发病机制、治疗及其预后。
关键词：
乳腺肿瘤；血管肉瘤；病理特征；癌基因；抑癌基因
Pathological features of primary breast angiosarcoma: A case report and literature review
CorrespondingAuthor: LU Yuanzhi Email: Yuanzhi.lu@jnu.edu.cn
DOI: 10.3978/j.issn.2095-6959.2021.04.038
Foundation: This work was supported by the National Natural Science Foundation of China (81572606).
Abstract
Primary breast angiosarcoma (PBA) is a rare malignant tumor of the breast. The pathological characteristics of PBA are diverse and usually exhibit an abnormally hyperplastic vascular-like structure. Due to unclear pathogenesis, nonspecific clinical manifestation, and great histological changes of the disease, it is a challenge for preoperative biopsy and intraoperative freezing diagnosis of PBA. This article will discuss the clinicopathological features, probable pathogenesis, treatment, and prognosis of PBA based on a case report and literature review.
Keywords：
breast neoplasms; angiosarcoma; pathological features; oncogenes; tumor suppressor genes