Objective: To explore the effect of the combination of medical education based on Internet technology in children with attention deficit hyperactivity disorder (ADHD). Methods: A hundred of children with ADHD who were treated in our hospital from May 2017 to April 2018 were selected as the subjects. According to the time sequence of admission, 50 children who were admitted from May to October 2017 were divided into the control group and given routine outpatient treatment; 50 children who were admitted from November 2017 to April 2018 were divided into the observation group, on the basis of routine treatment, they were treated with the combination of medicine and education based on Internet technology. The Chinese version of SNAP-IV and IVA-CPT were used to evaluate the changes of clinical symptoms and parents’ satisfaction with treatment before and after intervention. Results: There was no significant difference in the total score of SNAP-IV and the scores of all dimensions between the two groups before intervention (P>0.05). After the intervention, the total score of SNAP-IV and the scores of each dimension in the observation group were lower than those in the control group, the difference was statistically significant (P<0.05). The scores of each dimension quotient of IVA-CPT in the two groups before and after the intervention were not significantly different; the scores of each dimension quotient of IVA-CPT in the two groups after the intervention were significantly lower than those before the intervention (P<0.05). The scores of IVA-CPT quotients in the observation group were lower than those in the control group (P<0.05), and the parents’ satisfaction with treatment in the observation group was significantly higher than that in the control group (P<0.05). Conclusion: The combination of medicine and education based on Internet technology has a good effect in the treatment of ADHD children, and has a good clinical value.