Objective: To investigate the willingness to salt-restriction diet and the application value of group nursing model in patients with chronic kidney disease (CKD). Methods: The medical records of 180 patients with CKD in our hospital were prospectively studied. According to the health belief model, questionnaires of willingness to salt-restriction diet were designed. The willingness and compliance of patients to salt-restriction diet were observed, and the related factors influencing the patients’ willingness to salt-restriction diet were analyzed. According to the results, group activities were carried out to explore the application value of group nursing model in improving patients’ willingness to salt-restriction diet. Results: Univariate and multivariate analysis showed that education level, income, professional knowledge level and conscious symptoms were the independent factors influencing the patients’ willingness to salt-restriction diet (P<0.05). After nursing, the proportion of patients with good compliance in patients with CKD (83.33%) was significantly higher than that before nursing (P<0.05). Conclusion: There are problems such as low willingness to salt-restriction diet and poor compliance in patients with CKD. The implementation of group nursing is helpful to improve patients' willingness and compliance to salt-restriction diet.