Objective: To analyze clinicopathological features and observe the pathological type and distribution among breast neoplasms in Affiliated Hospital of Academy of Military Medical Sciences, according to the World Health Organization criteria (2008). Methods: A retrospective analysis of 2,392 cases of breast neoplasms, which was made by authors, from August 2009 to August 2014. All the histopathological slides including HE slides and immunohistochemistry slides were re-examined and the medical records were reviewed. Results: Among the 2,392 cases, most patients were female (2,382, 99.58%) and rare patients were male (10, 0.42%), 982 cases were benign tumor (41.05%), 1,389 were breast cancer or carcinoma in situ (58.07%), 10 were malignant or borderline phyllodes tumors (0.42%), 2 were lymphoma(0.08%), and 9 were metastase tumor (0.38%). Among the benign tumors, fibroadenoma, intraductal papilloma, benign phyllodes tumor, lipoma and tubular adenoma were more common in turn, the peak of fibroadenoma occurs in patients aged 20~40, while most of breast cancer were invasive ductal carcinoma 1,112 cases (87.63%), then lobular carcinoma (37, 2.91%), other special types cancer (120, 9.46%). Among breast cancer, infiltrating ductal carcinoma, invasive lobular carcinoma, basal-like breast cancer, mucinous carcinoma were more common in turn. The peak of invasive ductal carcinoma occurs in patients aged 40~60. Among breast cancer 693 cases were Luminal A type, 127 were Luminal B type, 130 were Her-2 type, 172 were normal breast-like type, and 21 were basal-like type. Conclusion: It is important to promote the early diagnosis of breast carcinoma by periodic inspection for early treatment breast neoplasms.