文章摘要

静默性垂体腺瘤的临床病理特征

作者: 1高 卫旭, 2战 华, 1姜 崴
1 哈尔滨医科大学附属第一医院内分泌科,哈尔滨 150001
2 哈尔滨医科大学附属第一医院神经外科,哈尔滨 150001
通讯: 姜 崴 Email: zhjiangwei@aliyun.com
DOI: 10.3978/j.issn.2095-6959.2019.09.025

摘要

无功能型垂体腺瘤(non-functional pituitary adenomas,NFPAs)是指缺乏垂体激素的分泌及激素分泌过多引起临床症状的垂体腺瘤。其中静默性垂体腺瘤是NFPAs的一种类型,是指免疫组织化学发现垂体激素免疫阳性,通常因为免疫组织化学结果或偶然检查被发现。不同类型的静默性垂体腺瘤具有各自的临床病理特征,本文对静默性垂体腺瘤的流行病学、影像学特征、临床表现与术后复发作一综述。
关键词: 无功能型垂体腺瘤;静默性垂体腺瘤;免疫组织化学

Clinicopathologic features of silent pituitary adenomas

Authors: 1GAO Weixu, 2ZHAN Hua, 1JIANG Wei
1 Department of Endocrinology, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
2 Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

CorrespondingAuthor:JIANG Wei Email: zhjiangwei@aliyun.com

Abstract

Non-functional pituitary adenoma refers to the pituitary adenoma that lacks the secretion of pituitary hormone and causes clinical symptoms by excessive secretion of hormone. Among them, silent pituitary adenoma is a type of non-functional pituitary adenoma, which means immunohistochemically found pituitary hormone immunopositively, and they are usually found because of immunohistochemical results or accidental examination. Different types of silent pituitary adenomas have their own clinicopathological features. This article reviews the epidemiology, imaging features, clinical manifestations and postoperative recurrence of silent pituitary adenomas.
Keywords: non-functional pituitary adenomas; silent pituitary adenoma; immunohistochemistry