文章摘要

电镜在心脏疾病中的研究及诊断意义

作者: 1孙洋, 2赵红
1 中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院,心血管疾病国家重点实验室实验诊断中心,北京 100037
2 中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院,心血管疾病国家重点实验室血栓性疾病中心,北京 100037
通讯: 赵红 Email: zhaohongfw@aliyun.com
DOI: 10.3978/j.issn.2095-6959.2017.07.035
基金: 院所特色项目基金, 2012-FWTS-03 院所青年基金, 2015-F05

摘要

心脏疾病的病因及发病机制复杂。随着生物医学研究手段的拓展,研究者需要将分子改变与表型建立联系,电子显微镜作为观察超微结构的成熟技术,在医学领域重新成为研究者们认识疾病的重要工具。
关键词: 电子显微镜 超微结构 心脏疾病

Research and diagnostic value of electron microscope in heart diseases

Authors: 1SUN Yang, 2ZHAO Hong
1 Department of Diagnostic Laboratory Service, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037
2 Thrombosis and Vascular Medicine Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China

CorrespondingAuthor: ZHAO Hong Email: zhaohongfw@aliyun.com

DOI: 10.3978/j.issn.2095-6959.2017.07.035

Abstract

The pathogenesis of heart diseases is very complicated. With biomedical techniques development, researchers need a bridge to connect molecular changes with phenotype. As a mature technology, electron microscope was reused as an important tool to understand diseases. This paper reviewed EM use in both basic research and clinical diagnosis.

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