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Aberrant Expression of PHLPP1 Correlates with Poor Prognosis in Patients with Gastric Cancer

  
@article{LCBL5591,
	author = {Ya-Chao  Hou 和 Han  Liang 和 Jing-Yu Deng},
	title = {Aberrant Expression of PHLPP1 Correlates with Poor Prognosis in Patients with Gastric Cancer},
	journal = {临床与病理杂志},
	volume = {35},
	number = {1},
	year = {2024},
	keywords = {},
	abstract = {Objective: The aim of this study was to investigate the expression of PHLPP1 in gastric cancer (GC), its potential influence on the prognosis of GC patients. Methods: In the present study, we examined the immunohistochemical expression of PHLPP1 on tissue microarrays (TMAs) containing 135 gastric adenocarcinoma tissues and 135 matched adjacent non-tumor tissues. Survival analysis according to PHLPP1 expression was calculated. Results: The majority of the adjacent non-tumor tissues showed positive-expression levels of PHLPP1 was 87.4% (118/135). In contrast, the positive rate of PHLPP1 in primary gastric cancer tissues was only 55.6% (75/135), significantly lower than that in adjacent non-tumor tissues (P},
	url = {https://lcbl.amegroups.com/article/view/5591}
}