@article{LCBL5564,
author = {Bi-bo Tan 和 Yu Liu 和 Dong Wang 和 Qun Zhao 和 Li-qiao Fan 和 Yong Li},
title = {Effect and mechanism of Vav3 gene to regulate inhibitor of apoptosis proteins in human gastri cancer cell line BGC823},
journal = {临床与病理杂志},
volume = {35},
number = {1},
year = {2024},
keywords = {},
abstract = {Objective: The purpose of this study is to examine expression of Vav3 and effect and mechanism of Vav3 gene to regulate inhibitor of apoptosis proteins in human gastri cancer cell line BGC823 is also explored. Methods: The expression of Vav3 in gastric cancer tissues and cell lines were detected. Specific siRNA targeting Vav3 were designed, synthesized, and transfected into BGC823. The expression of Vav3 was detected by real-time quantitative PCR and western blot Cytoactive was measured with MTT assay Cell apoptosis rate were determined by flow cytometry (FCM). The expressions of Survivin, c-IAP1, c-IAP2, XIAP, Livin and Caspase-3 were also determined. Results: Vav3 was significantly up-regulated in gastric cancer tissues and gastric cancer cell line (both P},
url = {https://lcbl.amegroups.com/article/view/5564}
}