@article{LCBL37140,
author = {雪蓉 蔡 和 学亚 张 和 敬新 潘},
title = {纤溶酶原激活物抑制剂-1的研究进展},
journal = {临床与病理杂志},
volume = {40},
number = {2},
year = {2020},
keywords = {},
abstract = {纤溶酶原激活物抑制剂-1(plasminogen activator inhibitor 1,PAI-1)作为体内组织型纤溶酶原激活物(tissue-type plasminogen activator,t-PA)和尿激酶型纤溶酶原激活物(urokinase-type plasminogen activator,u-PA)的主要抑制剂,与动静脉血栓、出血和凝血异常、细胞迁移密切相关,进而引起缺血性脑卒中、冠心病、静脉血栓、肿瘤转移、出血、股骨头坏死、流产等一系列疾病的发生发展。同时,体内血浆PAI-1活性水平又受血脂、血糖等调节,进一步参与肥胖、糖尿病、高脂血症等疾病的进程,又影响着上述相关疾病的预后。},
url = {https://lcbl.amegroups.com/article/view/37140}
}