@article{LCBL31233,
author = {倩倩 叶},
title = { SATB2 基因增强槲皮素抑制肾癌细胞生长的机制},
journal = {临床与病理杂志},
volume = {39},
number = {4},
year = {2019},
keywords = {},
abstract = {目的:探讨核基质蛋白特异AT序列结合蛋白2(special AT-rich sequence-binding protein 2,SATB2)基因及槲皮素对肾癌细胞活力、侵袭能力和凋亡的影响及机制。方法:人肾癌786-O细胞分为空白组、重组体pcDNA3.1-SATB2组、槲皮素组和pcDNA3.1-SATB2+槲皮素组,其中pcDNA3.1-SATB2转染参照Lipofectamine 2000说明。各组细胞处理48 h后,通过CCK-8,Transwell小室及流式细胞术分别检测细胞活力、侵袭能力和凋亡。Western印迹法检测SATB2,STAT3,p- STAT3,MMP-2和Bcl-2蛋白表达。结果:转染pcDNA3.1-SATB2的786-O细胞SATB2蛋白表达明显升高(P},
url = {https://lcbl.amegroups.com/article/view/31233}
}