@article{LCBL23099,
author = {艳荣 时 和 录克 李 和 文华 赵},
title = {弥漫大B细胞淋巴瘤治疗前 18 F-FDG PET/CT显像中肿瘤相关指标与乳酸脱氢酶及预后的相关性分析},
journal = {临床与病理杂志},
volume = {38},
number = {2},
year = {2018},
keywords = {},
abstract = {目的:探讨弥漫大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)治疗前18F-氟代脱氧葡萄糖(18F-fluorodeoxyglucose,18F-FDG) PET/CT显像中肿瘤相关指标与乳酸脱氢酶(lactate dehydrogenase,LDH)、预后的相关性。方法:选择经病理检查确诊的DLBCL患者78例,治疗前均行18F-FDG PET/CT,以Spearman相关性分析PET/CT显像中肿瘤相关指标[最大标准摄取值(maximum standard uptake value,SUVmax)、代谢体积(metabolic tumor volume,MTV)、病灶糖酵解总量(total glycolysis of lesions,TLG)]与LDH水平及预后相关因子[Ann Arbor分期、国际预后指数(international prognostic index,IPI)、结节受侵部位数]的关系。以无进展生存期(progression-free survival,PFS)为阳性事件,经受试者工作特征(receiver operating characteristic curve,ROC)曲线获取SUVmax,MTV,TLG最佳界值点;统计3年PFS,以Cox比例风险模型分析影响PFS的独立因素。结果:SUVmax与LDH,Ann Arbor分期、IPI评分、结节受侵部位数均无相关性(P>0.05);MTV,TLG与LDH水平、Ann Arbor分期、IPI评分显著均呈正相关(均P},
url = {https://lcbl.amegroups.com/article/view/23099}
}