2015 年第 35 卷第 4 期

AME科研时间专栏 AME Groups Column

埃博拉援非记——主动请战,临危受命,不辱使命
The story of aid to Africa during the Ebola outbreak-initiative accepting the challenge and successfully completing the mission
临床医生谈统计学应用
Clinicians discussing the application of statistics
德国医生的收入
Salaries of German doctors
王毅翔
Wáng Yì-Xiáng J.
AME指南解读 | 《中国原发性肺癌诊疗规范(2015年版)》更新要点
AME Interpreting Guidelines | Key points of the updated "Standards for the diagnosis and treatment of primary lung cancer (2015 version) in China"
CCO杂志被PubMed/Medline收录
Chinese Clinical Oncology is now indexed by PubMed/MEDLINE: a big step forward
APM杂志被PubMed/MEDLINE收录
APM being indexed in PubMed/MEDLINE
钟清华
Zhong Nancy Q.
跨癌肿新辅助治疗异同——CSCO青委新辅助治疗专场
Similarities and differences of neoadjuvant therapy among different sites of cancers
翟浩然, 钟文昭
ZHAI Haoran, ZHONG Wenzhao

泌尿生殖专题 Special Topic on Genitourinary System


Preface
郑军华
ZHENG Junhua
miR-155在肾结石患者血清和尿液中的表达及其临床意义
Expression and its clinical significance of miR-155 in serum and urine from patients with nephrolithiasis
胡洋洋, 李妍, 李伟, 牛晓振, 彭波, 刘敏
HU Yangyang, LI Yan, LI Wei, NIU Xiaozhen, PENG Bo, LIU Min
小鼠睾丸间质细胞分离培养方法的研究进展
Research progress in separation and culture of mouse Leydig cells
谢天承, 许云飞
XIE Tian Cheng, XU Yunfei
经皮肾镜取石术后发热的危险因素和防治措施
Risk factors of postoperative fever in percutaneous nephrolithotomy and optimal treatment strategy
王光春, 朱崴, 黄建华, 刘敏, 耿江, 鄢阳, 车建平, 牛晓振, 申佩军, 彭波, 许云飞, 姚旭东, 郑军华
WANG Guangchun, ZHU Wei, HUANG Jianhua, LIU Min, GENG Jiang, YAN Yang, CHE Jianping, NIU Xiaozhen, SHEN Peijun, PENG Bo, XU Yunfei, YAO Xudong, ZHENG Junhua
超声引导经皮肾镜取石术治疗孤立肾肾结石的安全性分析
Safety and curative effects of ultrasound-guided percutaneous nephrolithotomy for renal calculi in solitary kidneys
王光春, 周婷婷, 刘敏, 黄建华, 胡洋洋, 严佳胜, 杨斌, 罗明, 张海民, 彭波, 许云飞, 姚旭东, 郑军华
WANG Guangchun, ZHOU Tingting, LIU Min, HUANG Jianhua, HU Yangyang, YAN Jiasheng, YANG Bin, LUO Ming, ZHANG Haimin, PENG Bo, XU Yunfei, YAO Xudong, ZHENG Junhua
膀胱憩室癌1例报告及文献回顾
Carcinoma in bladder diverticula: a case report and literature review
黄建华, 彭波, 刘敏, 王光春, 姚旭东, 郑军华
HUANG Jianhua, PENG Bo, LIU Min, WANG Guangchun, YAO Xudong, ZHENG Junhua
泌尿外科腔镜术后尿源性脓毒血症的预后影响因素分析
The prognostic factors analysis of urosepsis after surgery with urologic endoscopy
张海民, 鄢阳, 许云飞, 彭波, 姚旭东, 郑军华
ZHANG Haimin, YAN Yang, XU Yunfei, PENG Bo, YAO Xudong, ZHENG Junhua
肿瘤相关胰蛋白酶抑制剂的研究概况
Advances of TATI and in tumors
王龙圣, 郑军华
WANG Longsheng, ZHENG Junhua
血清YKL-40蛋白水平与非肌层浸润性膀胱癌复发的临床关系研究
Clinical correlation between serum YKL-40 protein level and the recurrence of non muscle-invasive bladder cancer
严佳胜, 申佩军, 郑军华, 刘敏
YAN Jiasheng, SHEN Peijun, ZHENG Junhua, LIU Min
男性更年期综合征患者性腺轴功能变化及其与代谢综合征的关系的动物性实验研究
Animal experimental study of gonadal axis function changes in patients with male climacteric syndrome and the relationship with metabolic syndrome
牛晓振, 郑军华, 耿江, 车建平, 王光春, 夏盛强, 王波, 彭波
NIU Xiaozhen, ZHENG Junhua, GENG Jiang, CHE Jianping, WANG Guangchun, XIA Shengqiang, WANG Bo, PENG Bo
趋化因子在肾细胞癌中的研究进展
Research progress of chemokines in renal cell carcinoma
陈少军, 郑军华
CHEN Shaojun, ZHENG Junhua

论著 Original Article

16例肝脏未分化性胚胎性肉瘤术前误诊分析
Analysis of 16 cases misdiagnosed undifferentiated embryonal sarcoma of the liver
李妍卓, 蔡权宇, 贾宁阳, 陈栋, 陆伦, 程红岩
LI Yanzhuo, CAI Quanyu, JIA Ningyang, CHEN Dong, LU Lun, CHENG Hongyan
树突状纤维黏液样脂肪瘤的临床病理学分析
Clinicopathologic analysis of dendritic fibromyxolipoma
郭为伟, 黄维清, 韩增磊, 孔庆暖
GUO Weiwei, HUANG Weiqing, HAN Zenglei, KONG Qingnuan
M型磷脂酶A2受体及其抗体和Nephrin在不同类型膜性肾病患者的表达
The expression of PLA2R, anti-PLA2R and Nephrin in different types of membranous nephropathy
崔静, 张燕, 娄景秋, 李文娜, 邱世磊, 齐栋, 吕伟
CUI Jing, ZHANG Yan, LOU Jingqiu, LI Wenna, QIU Shilei, QI Dong, LV Wei
NALP3在低氧肺损伤大鼠肺组织中的表达及意义
Expression and significance of NALP3 in the hypoxic lung lnjury in rats
潘纯钰, 吴岳
PAN Chunyu, WU Yue
L-精氨酸对大鼠脂多糖致急性肺损伤的影响及机理
Effects and mechanism of L-Arginine on acute lung injury induced by LPS
范玉丽, 盛净, 朱健, 陆平
FAN Yuli, SHENG Jing, ZHU Jian, LU Ping
microRNA-208在急性心肌梗死患者外周血中的表达及意义
Changes of microRNA-208 level in plasma of acute myocardial infarction patient and its clinical significance
史万青, 高明珠, 韩志君
SHI Wanqing, GAO Mingzhu, HAN Zhijun
个性化护理在肝硬化患者中应用效果的研究
Research on personalized nursing application effect in patients with cirrhosis
王秀全, 王雪莲, 吴育云
WANG Xiuquan, WANG Xuelian, WU Yuyun
综合护理干预对心脏手术后患者疼痛的影响分析
The effect analysis of comprehensive nursing intervention on pain in patients after cardiac surgery
沈春林, 蔡谋善, 吴琼娅, 王非凡, 王琼
SHEN Chunlin, CAI Moushan, WU Qiongya, WANG Feifan, WANG Qiong
早期肠内营养支持治疗对重症脑出血患者免疫功能和预后指标的影响
Effect of early enteral nutrition on immune function and prognostic indicators of the patients with severe intracerebral hemorrhage
邱斌, 邢小珍, 肖展翅, 王洲羿
QIU Bin, XING Xiaozhen, XIAO Zhanchi, WANG Zhouyi
不同阶段的运动疗法对妊娠期糖尿病患者的长期预后作用
The prognosis for gestational diabetes mellitus patients according to different stages of physical activity
余蓓蓓, 肖冰, 金琳, 朱军
YU Beibei, XIAO Bing, JIN Lin, ZHU Jun
快速康复外科及早期肠内营养在胃癌术后患者治疗中的临床价值研究
Clinical value of fast track surgery and early enteral nutrition in the treatment of patients with gastric cancer
乐科发, 赵丽华, 洪和平, 徐辉照, 孙玲花, 孙桥樑
LE Kefa, ZHAO Lihua, HONG Heping, XU Huizhao, SUN Linghua, SUN Qiaoliang

临床病例讨论 Case Report

双侧重复肾输尿管畸形合并右侧后肾腺瘤1例并文献复习
The right renal metanephric adenoma with bilateral duplex kidney and ureter: a case report and literature review
李玉梅, 曹志星, 吴晓媚, 谢亚峰, 赵晔, 周宾, 吕威, 莫海波
LI Yumei, CAO Zhixing, WU Xiaomei, XIE Yafeng, ZHAO Ye, ZHOU Bin, LV Wei, MO Haibo
鼻腔平滑肌肉瘤1例及文献复习
Leiomyosarcoma of nasal cavity: a case report and literature review
张冬梅, 魏建国, 杨建峰
ZHANG Dongmei, WEI Jianguo, YANG Jianfeng

肺癌:筛查与诊断新方法 Lung Cancer: New Approaches to Screening and Diagnosis

肿瘤患者循环肿瘤细胞(CTCs)的分离工具:细胞角蛋白包被磁珠
CK-coated magnetic-based beads as a tool to isolate circulating tumor cells (CTCs) in human tumors
Clara Mayo, Francisco G. Ortega, Ana Giménez-Capitán, Miguel A. Molina-Vila, Maria José Serrano, Santiago Viteri, Carlota Costa, Amaya Gascó, Jordi Bertran-Alamillo, iki Karachaliou, José Antonio Lorente, Miquel Tarón, Rafael Rosell
Mayo Clara, Ortega Francisco G., Giménez-Capitán Ana, Molina-Vila Miguel A., Serrano Maria José, Viteri Santiago, Costa Carlota, Gascó Amaya, Bertran-Alamillo Jordi, Karachaliou Niki, Lorente José Antonio, Tarón Miquel, Rosell Rafael
全面分子筛选:从RT-PCR 到RNA 测序
Comprehensive molecular screening: from the RT-PCR to the RNA-seq
Carlota Costa, Ana Giménez-Capitán, iki Karachaliou, Rafael Rosell
Costa Carlota, Giménez-Capitán Ana, Karachaliou Niki, Rosell Rafael
纤维母细胞生长因子受体1(FGFR1) 的扩增:肺鳞状细胞癌中诊断和治疗应
FGFR1 amplifications in squamous cell carcinomas of the lung: diagnostic and therapeutic implications
Hans-Ulrich Schildhaus, Lucia ogova, Jürgen Wolf, Reinhard Buettner
Schildhaus Hans-Ulrich, Nogova Lucia, Wolf Jürgen, Buettner Reinhard

肺癌:治疗新靶点 Lung Cancer: New Targets for Therapy

HER2 驱动非小细胞肺癌(NSCLC):潜在的治疗路径
HER2 driven non-small cell lung cancer (NSCLC): potential therapeutic approaches
Ana Christina Garrido-Castro, Enriqueta Felip
Garrido-Castro Ana Christina, Felip Enriqueta
靶向EML4-ALK 驱动的非小细胞肺癌
Targeting EML4-ALK driven non-small cell lung cancer (NSCLC)
Teresa Morán, Vanesa Quiroga, María de los Llanos Gil, Laia Vilà, uria Pardo, Enric Carcereny, Laia Capdevila, Ana M Muñoz- Mármol, Rafael Rosell
Morán Teresa, Quiroga Vanesa, de los Llanos Gil María, Vilà Laia, Pardo Nuria, Carcereny Enric, Capdevila Laia, Muñoz- Mármol Ana M, Rosell Rafael
KRAS 突变的非小细胞肺癌: 一种新的合成致死作用方法
KRAS mutant NSCLC, a new opportunity for the synthetic lethality therapeutic approach
Javier de Castro Carpeño, Cristóbal Belda-Iniesta
de Castro Carpeño Javier, Belda-Iniesta Cristóbal
SOX2 在非小细胞肺癌,肺腺癌和肺鳞癌中的作用
The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung
iki Karachaliou, Rafael Rosell, Santiago Viteri
Karachaliou Niki, Rosell Rafael, Viteri Santiago

肺癌:治疗方法新发展 Lung Cancer: Recent Advances in Therapy

转移性非小细胞肺癌的个体化化疗
Customized chemotherapy in metastatic non-small cell lung cancer (NSCLC)
Jia Wei, Teresa Moran, Zhengyun Zou, Xiaoping Qian, Lifeng Wang, Carlos Camps, Wenjing Hu, Imane Chaib, Belén Sanchez, Lixia Xu, iki Karachaliou, María Sanchez-Ronco, Baorui Liu, Rafael Rosell
Wei Jia, Moran Teresa, Zou Zhengyun, Qian Xiaoping, Wang Lifeng, Camps Carlos, Hu Wenjing, Chaib Imane, Sanchez Belén, Xu Lixia, Karachaliou Niki, Sanchez-Ronco María, Liu Baorui, Rosell Rafael
老年肺癌患者的治疗
Management of elderly patients
Alain Vergnenegre, Romain Corre, Hervé Lena, Hervé Le Caer
Vergnenegre Alain, Corre Romain, Lena Hervé, Le Caer Hervé
放疗的发展现状
State of the art of radiotherapy
Pilar Garrido, Mª Eugenia Olmedo
Garrido Pilar, Olmedo Mª Eugenia
细胞凋亡药物
Apoptotic agents
Dean A. Fennell
Fennell Dean A.
肿瘤靶向治疗中的适应性耐药
Adaptive resistance to targeted therapies in cancer
Rafael Rosell, iki Karachaliou, Daniela Morales-Espinosa, Carlota Costa, Miguel Angel Molina, Irene Sansano, Amaya Gasco, Santiago Viteri, Bartomeu Massuti, Jia Wei, María González Cao, Alejandro Martínez Bueno
Rosell Rafael, Karachaliou Niki, Morales-Espinosa Daniela, Costa Carlota, Molina Miguel Angel, Sansano Irene, Gasco Amaya, Viteri Santiago, Massuti Bartomeu, Wei Jia, Cao María González, Martínez Bueno Alejandro

肺癌:预测与预后的分子标志物 Lung Cancer: Predictive and Prognostic Molecular Markers

在鳞状细胞肺癌中FGFR1 与3 号染色体长臂的拷贝数增加
Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung
Pedro Mendez, Jose Luis Ramirez
Mendez Pedro, Ramirez Jose Luis
晚期非小细胞肺癌个体化化疗的预测因子
Predictive models for customizing chemotherapy in advanced non-small cell lung cancer (NSCLC)
Laura Bonanno
Bonanno Laura
我们准备好使用分子标志物来确定早期非小细胞肺癌的分期、预后和选择治疗方案吗?
Are we ready to use biomarkers for staging, prognosis and treatment selection in early-stage non-small-cell lung cancer?
Bartomeu Massuti, Jose Miguel Sanchez, Florentino Hernando-Trancho, iki Karachaliou, Rafael Rosell
Massuti Bartomeu, Sanchez Jose Miguel, Hernando-Trancho Florentino, Karachaliou Niki, Rosell Rafael
肿瘤异质性:EGFR 突变型非小细胞肺癌患者的时空演变
Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients
Margarita Majem, Jordi Remon
Majem Margarita, Remon Jordi
非洲裔美国人非小细胞肺癌患者EGFR 分子检测:文献间结果矛盾
EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data
Bradley T. Clifford, Pingfu Fu, athan Pennell, Balazs Halmos, Rom S. Leidner
Clifford Bradley T., Fu Pingfu, Pennell Nathan, Halmos Balazs, Leidner Rom S.
14个预后基因确认的I 期高危非鳞癌患者辅助化疗的全球性试验
International trial of adjuvant therapy in high risk stage I non-squamous cell carcinoma identified by a 14-gene prognostic signature
Johannes R. Kratz, Michael J. Mann, David M. Jablons
Kratz Johannes R., Mann Michael J., Jablons David M.