目的：研究378例早期胃癌(early gastric cancer，EGC)的病理特征及临床意义。方法：回顾分析2012年8月至2014年8月河北医科大学第四医院378例EGC标本的肿瘤直径、浸润深度、肉眼分型、组织学分型、淋巴结转移进行检查。结果：全组病例男性312例，女性66例；182例肿瘤局限在粘膜层，196例侵及粘膜下层；发生部位主要位于贲门222例(58.73%)；肉眼分型以Ⅱ型为主(53.44%)；组织学类型以管状腺癌为主(77.25%)；出现淋巴结转移20例(5.29%)。结论：浸润深度、组织学类型、淋巴结转移等是EGC组织病理学诊断的重要指标。
Pathological characteristics of early gastric cancer: an analysis of 378 cases
Objective: To investigate the pathological characteristics of 378 cases of early gastric cancer (EGC) and the related clinical significance. Methods: 378 cases of early gastric cancer from August 2012 to August 2014 were examined. We detected the tumor diameter, depth of invasion, gross type, histological type, and lymph node metastasis. Results: There were 312 male and 66 female patients. The cancerous tissue were limited to mucosa in 182 cases and invaded into submucosa in other 196 cases. Early gastric cancer was mainly located in cardia (58.73%), and was mainly types II (53.44%) in grossly. Histologically, great majority cases were tubular adenocarcinoma (77.25%). The incidence of lymph node metastases was 5.29% (20 of 378 cases). Conclusion: Invasion depth, histological types, and lymph node metastasis were all import index for pathological diagnosis in patients with early gastric cancer.