综述 Review

血管内NK/T细胞淋巴瘤的研究进展

Published at: 2017年第37卷第9期

徐嘉雯 1 , 王宏量 2 , 赵文博 3 , 曹智新 1
1 山东大学附属省立医院病理科,济南 250021
2 山东省职业卫生与职业病防治研究院,山东省医学科学院,济南 250062
3 山东大学附属省立医院血液科,济南 250021
通讯作者 智新 曹 Email: caozhixin12@126.com
DOI: 10.3978/j.issn.2095-6959.2017.09.028
基金:
国家自然科学基金 81202092
山东省重点研发计划项目 2015GSF118015,2016GSF201087

摘要

血管内NK/T细胞淋巴瘤(intravascular NK/T cell lymphoma,IVNKTL)罕见,其特征性表现为肿瘤性淋巴细胞选择性生长于血管腔内。不同地域患者临床表现多样且缺乏特异性,因此临床诊断困难。IVNKTL具有病程进展快、伴EBV感染、好发于亚洲,且以中国人多发等特点。在肿瘤未累及到多器官前进行早期诊治可有效改善IVNKTL患者的预后。


Research progress in intravascular NK/T cell lymphoma

Abstract

Intravascular NK/T cell lymphoma (IVNKTL) is a rare type of malignant lymphoma characterized by the selective growth of neoplastic lymphocytes within the lumina of blood vessels. The clinical manifestations are diverse and non-specific in different geographical areas, making diagnosis difficult. IVNKTL is a highly aggressive and EBV-associated lymphoma that is prone to develop in Asian patients, particularly in Chinese patients. Early diagnosis and treatment before multi-organ involvement could effectively improve the prognosis of IVNKTL patients.


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引用

引用本文: 嘉雯 徐, 宏量 王, 文博 赵, 智新 曹. 血管内NK/T细胞淋巴瘤的研究进展[J]. 临床与病理杂志, 2017, 37(9): 1932-1935.
Cite this article as: XU Jiawen, WANG Hongliang, ZHAO Wenbo, CAO Zhixin . Research progress in intravascular NK/T cell lymphoma[J]. Journal of Clinical and Pathological Research, 2017, 37(9): 1932-1935.