临床病例讨论 Case Analysis

泛发性皮肤肌纤维瘤1例并文献复习

Published at: 2017年第37卷第9期

陈尚周 1 , 陈思远 2 , 雷淑英 1
1 恩施州土家族苗族自治州中心医院皮肤科,湖北 恩施 445000
2 华中科技大学同济医学院附属协和医院皮肤科,武汉 430022
通讯作者 淑英 雷 Email: shuyinglei@yahoo.com
DOI: 10.3978/j.issn.2095-6959.2017.09.041
基金:

摘要

报道1例泛发性皮肤肌纤维瘤,并对国内外相关文献进行复习回顾。本例患者以躯干泛发暗红色丘疹、斑块、结节为主要临床表现。病理见真皮内界限清晰的结节,梭形细胞周围充盈嗜伊红染色的胶原纤维。免疫组织化学:波形蛋白(vimentin)和平滑肌肌动蛋白(smooth muscle actin,SMA)均为阳性,CD34局灶性阳性,结蛋白(Desmin)和S-100均阴性。根据临床表现,组织病理和免疫组织化学结果可诊断。


Generalized dermatomyofibroma: A case report and literature review

Abstract

We described a case of generalized dermatomyofibroma and reviewed the domestic and international interrelated literatures. There were many dark red papules, plaques and nodules in the trunk as the main clinical manifestation. Histopathological features of the lesions on low back showed the nodule localized in the dermis with clear edges. There were many spindle cells surrounded by abundant eosinophilic staining of collagen fibers. Immunohistochemistry results showed the tumor cells were positive for vimentin and smooth muscle actin, focally positive for CD34, but negative for desmin and S-100. It was diagnosed as dermatomyofibroma according to the clinical, histopathological and immunohistochemical findings.


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引用

引用本文: 尚周 陈, 思远 陈, 淑英 雷. 泛发性皮肤肌纤维瘤1例并文献复习[J]. 临床与病理杂志, 2017, 37(9): 2009-2012.
Cite this article as: CHEN Shangzhou, CHEN Siyuan, LEI Shuying . Generalized dermatomyofibroma: A case report and literature review[J]. Journal of Clinical and Pathological Research, 2017, 37(9): 2009-2012.