A case report of splenectomy for a patient with primary myelofibrosis misdiagnosed as hypersplenism
Objective: To study the diagnosis and differential diagnosis of primary myelofibrosis (PMF). Methods: The clinical data, bone marrow pathological and gene studies of one case of PMF were organized. And then we learned its pathological diagnosis and differential diagnosis combined with literature. Results: The hematopoietic function is poor in PMF patients. Liver and spleen enlargement is the body compensatory reaction, but not because of hypersplenism. We cannot do splenectomy when the diagnosis is not clear. Conclusion: For those patients with unexplained splenomegaly, diagnosis evidence should be adequate. The clinical and histological features combined with bone marrow smear, biopsy and gene detection can contribute to its diagnosis and differential diagnosis.