目的：通过分析2例慢性血栓栓塞性肺动脉高压(chronic thromboembolic pulmonary hypertension，CTEPH)的女性病人的病例报告以及循证国内外研究结果，提高对罕见的与子宫肌瘤相关的CTEPH的认识，提高肺动脉高压的诊治水平。方法：病例报告及文献检索。结果：既往有子宫肌瘤的女性肺动脉高压患者，临床发现肺动脉血栓形成，诊断为CTEPH，CTEPH发病可能与子宫肌瘤相关。结论：慢性血栓栓塞性肺动脉高压和/或肺动脉高压可能是子宫肌瘤一种罕见的并发症。在临床实践中应考虑其可能性，尽早给予病人子宫肌瘤剔除术治疗及抗血栓治疗，提高治疗水平。
Case report of chronic thromboembolic pulmonary hypertension: is it associated with uterine myoma?
Objective: By reporting 2 female cases of chronic thromboembolic pulmonary hypertension (CTEPH) and reviewed the research results in China and abroad, this study aims to improve the understanding of rare CTEPH associated with uterine myoma and to improve the diagnosis and treatment of pulmonary hypertension. Methods: We reported the two cases and reviewed the related literatures. Results: The female pulmonary hypertension patients with a history of uterine myoma were diagnosed as CTEPH. The incidence of CTEPH may be associated with uterine myoma. Conclusion: CTEPH and/or pulmonary hypertension is a rare complication of myoma, however, they should be considered in clinical practice. Thrombolytic therapy associated with myomectomy can be implemented for treating such cases.