论著 Original Article

内镜下低温等离子射频消融术与常规喉裂开术治疗早期声门型喉癌疗效的对比分析

Published at: 2016年第36卷第12期

卢大松 1 , 冯勇军 1 , 曾春荣 1 , 王明靖 1
1 海南省农垦总医院耳鼻咽喉头颈外科,海口 570311
通讯作者 大松 卢 Email: lida84107@126.com
DOI: 10.3978/j.issn.2095-6959.2016.12.016
基金:
海南省卫生厅科学研究课题 琼卫2012PT-35

摘要

目的:分析内镜下低温等离子射频消融术与常规垂直半喉切除术治疗早期声门型喉癌疗效。方法:选取本院2011年2月至2014年2月收治的100例早期声门型喉癌患者,参照抽签法分作对照组和治疗组,各50例,对照组采用常规喉裂开术治疗,治疗组采用内镜下低温等离子射频消融术治疗,比较两组的手术情况、语音变化、并发症、声带黏膜恢复情况、复发率。结果:治疗组术中出血量、手术时间、住院时间均优于对照组(P<0.05);术后1个月,治疗组语音情况(基频微扰、振幅微扰、谐噪比)[(1.15±0.12)%,(2.61±0.33)%,(22.30±3.74) dB]优于对照组[(1.27±0.16)%,(4.29±0.38)%,(20.12±3.22) dB],比较差异有统计学意义(P<0.05);治疗组总并发症率(3/50,6.00%)低于对照组(10/50,20.00%),比较差异有统计学意义(P<0.05);治疗组声带黏膜光滑率(47/50,94.00%)高于对照组(30/50,60.00%;P<0.05);两组复发率比较差异无统计学意义(P>0.05)。结论:内镜下低温等离子射频消融术治疗早期声门型喉癌的效果确切,能够显著改善患者的语音情况,同时术后并发症少,复发率低,值得推广。


Curative effect analysis of endoscopy low-temperature plasma radiofrequency ablation and normal laryngeal crack treatment in early glottis type of throat cancer

Abstract

Objective: To analysis the curative effect of endoscopy low-temperature plasma radiofrequency ablation and normal laryngeal crack treatment in early glottis type of throat cancer. Methods: 100 cases of early glottic cancer from February 2011 to February 2014 in our hospital were analyzed and divided into control group (50 cases) and treatment group (50 cases) due to the draw method. The control group was treated with normal larynx crack treatment; the treatment group was carried out by endoscopic low-temperature plasma radiofrequency ablation. Observed the situation of surgery of two groups, voice changes, vocal mucosa recovery, complications and recurrence rate were compared. Results: The intraoperative blood loss, operative time, length of hospital stay of treatment group were better than those of control group (P<0.05); 1 month after operation, the speech situation (fundamental frequency perturbation, amplitude perturbation, harmonic noise ratio) of the treatment group was 1.15%±0.12%, 2.61%±0.33%, (22.30±3.74) dB, which were better than those of the control group [1.27%±0.16%, 4.29%±0.38%, (20.12±3.22) dB], the difference between two groups was significant (P<0.05); the total complication rate (6.00%, 3/50) of treatment group is lower than that of the control group (20.00%, 10/50), the difference was significant (P<0.05); vocal mucosa smooth rate (94.00%, 47/50) of treatment group was higher than that of the control group (60.00%, 30/50; P<0.05); the recurrence of two groups had no difference (P>0.05). Conclusion: The endoscopic low-temperature plasma radiofrequency ablation for treating early glottis cancer can significantly improve voice situation of patient, at the same time, it has less postoperative complications and lower recurrence rate, which is worth promoting.


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引用

引用本文: 大松 卢, 勇军 冯, 春荣 曾, 明靖 王. 内镜下低温等离子射频消融术与常规喉裂开术治疗早期声门型喉癌疗效的对比分析[J]. 临床与病理杂志, 2016, 36(12): 1975-1980.
Cite this article as: LU Dasong, FENG Yongjun, ZENG Chunrong, WANG Mingjing . Curative effect analysis of endoscopy low-temperature plasma radiofrequency ablation and normal laryngeal crack treatment in early glottis type of throat cancer[J]. Journal of Clinical and Pathological Research, 2016, 36(12): 1975-1980.