目的：探讨中毒性表皮坏死松解型药疹(toxic epidermal necrolysis，TEN)的护理措施。方法：对9例TEN患者实施保护性隔离，在积极支持治疗的基础上，采用纳米银抗感染敷料联合无菌棉垫覆盖创面，安排特护确保基础护理、创面护理、病情观察到位。结果：9例患者均未发生创面感染，经过精心治疗护理原有感染创面治愈，8例痊愈出院未遗留疤痕，1例因多器官功能衰竭死亡。结论：在合理治疗的基础上，实施精心护理是提高TEN患者抢救成功率、降低创面感染、遗留疤痕等的重要策略。
Nursing care of the patients who had caught toxic epidermal necrolysis
Objective: To investigate the nursing methods of skin mucosa for toxic epidermal necrolysis (TEN) epidermolysis and exfoliative patients in large area. Methods: Nine TEN hospitalized patients put under quarantine, with actively support treatment, were applied with the combination of nano-silver ion dressing and sterile pad to covering the wound. Intensive care and a strict watch were supported by the nursing experts in intensive care wards. Results: All 9 cases don’t get any skin mucosa infection, and 8 of them are discharged from hospital with good recovery of their skins and no scars or pigmentation. But the ninth one died from multiple organ failure. Conclusion: Based on the reasonable treatment, careful nursing was the key measures to increase survival of patients with TEN, reduce the rate of wound infection and scars or pigmentation occurrence.