Comparison of the effects, survival quality and time between radical operation and palliative operation in treating patients with TNM Ⅲ stage pancreatic cancer
Objective: To compare the effects, survival quality and time between radical operation and palliative operation in treating patients with TNM Ⅲ stage pancreatic cancer. Methods: Sixty patients with Ⅲ stage pancreatic cancer who were treated in our hospital between January 2011 and December 2014 were divided into radical operation group (group A, n=34) and palliative operation group (group B, n=26). The incidence of postoperative complications, survival quality and postoperative 1-, 2- and 3-year survival rates were compared between two groups. Results: There were no significant differences in Clavien Ⅲ, Clavien Ⅳ and incidence of pancreatic fistula between two groups after operation (P>0.05); the incidence rate of Clavien Ⅱ in group A (41.2%) was significantly higher than group B (15.4%) (P<0.05). Quality of life scores in group A were higher than group B (P<0.05). The 1-, 2- and 3-year survival rates in group A were 44.2%, 21.2% and 16.1% respectively, while in group B were 15.4%, 8.0% and 0, respectively (P>0.05). Conclusion: The effect of radical operation in the treatment of patients with TNM Ⅲ stage pancreatic cancer is better, and the postoperative 1-, 2- and 3-year survival rates are higher than palliative operation. The quality of life is higher and it will not increase postoperative complications.