论著 Original Article

风湿性心脏病伴发脑栓塞患者脑血流动力学初探

Published at: 2016年第36卷第9期

姜建 1 , 刘煜敏 1 , 孔朝红 1 , 任善玲 1
1 武汉大学中南医院神经科,武汉 430070
通讯作者 煜敏 刘 Email: lym9381@126.com
DOI: 10.3978/j.issn.2095-6959.2016.09.008
基金:

摘要

目的:研究风湿性心脏病伴发血栓脱落致脑栓塞(stroke caused by thrombosis of rheumatic heart disease,RHD)患者的血流动力学特征。方法:用经颅多普勒超声(transcranial Doppler,TCD)连续观查30例确诊的风湿性心脏病伴发血栓脱落致脑栓塞患者,另选同期在我院体检中心体检的正常患者60例进行对照。结果:RHD患者主要表现为椎基底动脉收缩期血流缓慢、脉动指数降低、Vp和Vm间的差距变小、波峰圆钝、多数患者出现频窗充填。除Vd值以外,两组病人左右椎动脉和基底动脉的Vp、Vm、PI值间均存在显著性差异(P<0.05)。结论:RHD患者的血流动力学表现具有相对的特异性,TCD可作为其临床初步筛查和辅助诊断手段之一。


Evaluation of hemodynamics in stroke patients caused by thrombosis of rheumatic heart disease

Abstract

Objective: To study the hemodynamic character in stroke patients caused by thrombosis of rheumatic heart disease (RHD). Methods: 30 cases of RHD were examined with transcranial Doppler (TCD), and meanwhile, 60 normal patients were also examined with TCD as control. Results: The hemodynamic character in vertebral basilar artery in patients with RHD mainly showed slower systolic blood flow, more decreased pulsating index and smaller gap between the Vp and Vm, which displayed rounded peaks and the frequency window of filling. There were significantly differences in Vp, Vm, PI values of the vertebral artery and basilar artery between the two groups (P<0.05), while the Vd value had no such difference. Conclusion: The patients with RHD had relative specificity hemodynamic character, and TCD can be used as an initial screening and diagnosis means of RHD.


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引用

引用本文: 建 姜, 煜敏 刘, 朝红 孔, 善玲 任. 风湿性心脏病伴发脑栓塞患者脑血流动力学初探[J]. 临床与病理杂志, 2016, 36(9): 1283-1287.
Cite this article as: JIANG Jian, LIU Yumin, KONG Zhaohong, REN Shanling . Evaluation of hemodynamics in stroke patients caused by thrombosis of rheumatic heart disease[J]. Journal of Clinical and Pathological Research, 2016, 36(9): 1283-1287.