论著 Original Article

维生素D3——非糖尿病肾病慢性肾脏病合并糖尿病的预测因子

Published at: 2017年第37卷第1期

李宝来 1
1 内蒙古林业总医院肾内科,内蒙古 牙克石 022150
通讯作者 宝来 李 Email: libaolai1026@163.com
DOI: 10.3978/j.issn.2095-6959.2017.01.001
基金:

摘要

目的:研究非糖尿病肾病慢性肾脏病(non-diabetes chronic kidney diseases,ND-CKD)3~5期患者合并糖尿病的相关因素,并用体内维生素D3水平来预测其风险。方法:对ND-CKD3~5期患者的糖尿病发生指标和维生素D3水平进行相关性分析,应用多项logistic回归分析,得出不同水平的维生素D3的ND-CKD合并糖尿病的概率值。结果:ND-CKD3~5期患者体内的维生素D3水平和餐后2 h血糖有负相关性(r=–0.430,P=2.07×10–5);该人群体内维生素D3在0~99.9,100.0~199.9,200.0~299.9 nmol/L三个水平合并糖尿病的概率分别为0.393,0.227,0.154。结论:维生素D3作为ND-CKD合并糖尿病的预测因子,有一定的临床意义。


Vitamin D3—a prognostic factor for non-diabetes chronic kidney diseases

Abstract

Objective: To identify the relevant factor of non-diabetes-chronic kidney disease (ND-CKD) 3—5 phrase and apply vitamin D3 to predict its risk. Methods: A correlation analysis of vitamin D3 and parameters of diabetic occurrence were made and a logistic regression analysis was applied to work out probability value of ND-CKD in different vitamin D3 levels between occurrence indicators of patient in ND-CKD 3—5 phrase and vitamin D3 level. Results: There was a negative correlation with statistically significant difference (correlation coefficient was −0.430, P=2.07×10–5) between vitamin D3 and serum glucose 2 h after oral glucose tolerance in ND-CKD patients. The rate of diabetic occurrence in ND-CKD patients with three different vitamin D3 levels (0—99.9, 100.0—199.9, 200.0—299.9 nmol/L) were estimated respectively as 0.393, 0.227 and 0.154 due to logistic analytic results. Conclusion: There is clinical significance for vitamin D3 to be a prognostic factor for ND-CKD.


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引用

引用本文: 宝来 李. 维生素D3——非糖尿病肾病慢性肾脏病合并糖尿病的预测因子[J]. 临床与病理杂志, 2017, 37(1): 1-4.
Cite this article as: LI Baolai . Vitamin D3—a prognostic factor for non-diabetes chronic kidney diseases[J]. Journal of Clinical and Pathological Research, 2017, 37(1): 1-4.